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QuickView for SLC22A5 (gene)


Gene Symbol:
SLC22A5 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 (organic cation/carnitine transporter), member 5
Synonyms:
organic cation transporter 2, organic cation transporter 5, organic cation/carnitine transporter 2, OCTN2, OCTN2VT, solute carrier family 22 (organic cation transporter), member 5, solute carrier family 22 (organic cation/carnitine transporter), member 5, solute carrier family 22 member 5, CDSP, high-affinity sodium dependent carnitine cotransporter, FLJ46769
Genomic Location:
Chr 5: 131733343-131759205
Description:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-de...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 5
5q23.3


Transcripts Names
NM_003060
Protein Names
B2R844
Q96EH6
Q6ZQZ8
O76082
D3DQ87



GO Molecular Function

drug transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | amine transmembrane transporter activity | binding | symporter activity | protein domain specific binding | ATP binding | adenyl nucleotide binding | cation transmembrane transporter activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | organic cyclic compound binding | drug transmembrane transporter activity | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | secondary active transmembrane transporter activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | PDZ domain binding | adenyl ribonucleotide binding | carnitine transporter activity | heterocyclic compound binding | quaternary ammonium group transmembrane transporter activity | small molecule binding | antibiotic transporter activity

GO Biological Process

regulation of biological process | interspecies quorum sensing | establishment of localization | regulation of biological quality | organic cation transport | response to drug | drug transporter activity | sodium-dependent organic cation transport | cellular process | localization | metal ion transport | regulation of digestive system process | regulation of intestinal epithelial structure maintenance | interspecies interaction between organisms | regulation of system process | transmembrane transporter activity | positive regulation of intestinal epithelial structure maintenance | response to stimulus | response to chemical stimulus | transport | quorum sensing involved in interaction with host | amine transmembrane transporter activity | amine transport | symporter activity | positive regulation of multicellular organismal process | ion transmembrane transport | interaction with host | organic substance transport | sodium ion transport | cation transmembrane transporter activity | amino-acid betaine transport | monovalent inorganic cation transport | active transmembrane transporter activity | transporter activity | multi-organism process | positive regulation of digestive system process | ion transmembrane transporter activity | homeostasis of number of cells | biological regulation | nitrogen compound transport | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | positive regulation of biological process | drug transmembrane transporter activity | homeostatic process | quorum sensing | positive regulation of homeostatic process | regulation of multicellular organismal process | carnitine transport | regulation of homeostatic process | secondary active transmembrane transporter activity | homeostasis of number of cells in a free-living population | drug transport | substrate-specific transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | drug transmembrane transport | cation transport | quaternary ammonium group transport | symbiosis, encompassing mutualism through parasitism | carnitine transporter activity | ion transport | antibiotic transport | quaternary ammonium group transmembrane transporter activity | antibiotic transporter activity

GO Cellular Component

brush border | integral to membrane | plasma membrane part | apical plasma membrane | cell projection membrane | cell | intrinsic to membrane | cell projection part | brush border membrane | apical part of cell | cell projection | plasma membrane | membrane part | cell part | cell periphery | basolateral plasma membrane | membrane