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QuickView for SLC22A4 (gene)


Gene Symbol:
SLC22A4 Homo sapiens Homo sapiens
Full name:
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
Synonyms:
solute carrier family 22 (organic cation/ergothioneine transporter), member 4, solute carrier family 22 member 4, ergothioneine transporter, ET transporter, integral membrane transport protein, MGC34546, MGC40524, OCTN1, organic cation/carnitine transporter 1
Genomic Location:
Chr 5: 131658044-131707798
Description:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 5
5q31.1


Transcripts Names
NM_003059
Protein Names
Q9H015
O14546



GO Molecular Function

ribonucleotide binding | transmembrane transporter activity | nucleotide binding | amine transmembrane transporter activity | binding | symporter activity | protein domain specific binding | ATP binding | adenyl nucleotide binding | cation transmembrane transporter activity | antiporter activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | solute:cation antiporter activity | cation:cation antiporter activity | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | organic cyclic compound binding | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | secondary active transmembrane transporter activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | PDZ domain binding | adenyl ribonucleotide binding | carnitine transporter activity | heterocyclic compound binding | quaternary ammonium group transmembrane transporter activity | small molecule binding | secondary active organic cation transmembrane transporter activity

GO Biological Process

establishment of localization | regulation of biological quality | organic cation transport | cellular process | secretion | localization | metal ion transport | triglyceride metabolic process | transmembrane transporter activity | cellular lipid metabolic process | transport | amine transmembrane transporter activity | cellular nitrogen compound metabolic process | amine transport | symporter activity | nitrogen compound metabolic process | lipid metabolic process | ion transmembrane transport | amino-acid betaine metabolic process | organic substance transport | sodium ion transport | cation transmembrane transporter activity | amino-acid betaine transport | monovalent inorganic cation transport | antiporter activity | single-organism process | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | carnitine metabolic process | solute:cation antiporter activity | biological regulation | cation:cation antiporter activity | nitrogen compound transport | substrate-specific transmembrane transporter activity | organic cation transmembrane transporter activity | glycerolipid metabolic process | neutral lipid metabolic process | metabolic process | carnitine transport | primary metabolic process | regulation of body fluid levels | body fluid secretion | secondary active transmembrane transporter activity | substrate-specific transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | cation transport | quaternary ammonium group transport | single-multicellular organism process | carnitine transporter activity | ion transport | cellular metabolic process | quaternary ammonium group transmembrane transporter activity | acylglycerol metabolic process | secondary active organic cation transmembrane transporter activity | multicellular organismal process

GO Cellular Component

integral to membrane | intracellular membrane-bounded organelle | plasma membrane part | apical plasma membrane | cell | intrinsic to membrane | cytoplasm | intracellular organelle | apical part of cell | plasma membrane | mitochondrion | membrane part | integral to plasma membrane | cell part | membrane-bounded organelle | organelle | cell periphery | cytoplasmic part | intracellular part | intracellular | membrane | intrinsic to plasma membrane