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QuickView for SLC10A1 (gene)


Gene Symbol:
SLC10A1 Homo sapiens Homo sapiens
Full name:
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
Synonyms:
Na(+)/bile acid cotransporter, Na(+)/taurocholate transport protein, Na/taurocholate cotransporting polypeptide, NTCP, NTCP1, sodium/bile acid cotransporter, sodium/taurocholate cotransporter, sodium/taurocholate cotransporting polypeptide, solute carrier family 10 (sodium/bile acid cotransporter family), member 1, solute carrier family 10 member 1, solute carrier family 10, member 1, GIG29, growth-inhibiting protein 29, cell growth-inhibiting gene 29 protein
Genomic Location:
Chr 14: 69312305-69333707
Description:
Sodium/bile acid cotransporters are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids, one absorbing from the intestinal lumen, the bile duct, and the kidney with an apical localization (SLC10A2; MIM 601295), and the other being...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 14
14q24.1


Transcripts Names
NM_003049
Protein Names
Q14973
Q2TU29
B2RA41
B9EGB6



GO Molecular Function

bile acid transmembrane transporter activity | bile acid:sodium symporter activity | transmembrane transporter activity | organic acid transmembrane transporter activity | symporter activity | cation transmembrane transporter activity | active transmembrane transporter activity | transporter activity | ion transmembrane transporter activity | solute:cation symporter activity | organic acid:sodium symporter activity | substrate-specific transmembrane transporter activity | carboxylic acid transmembrane transporter activity | metal ion transmembrane transporter activity | monocarboxylic acid transmembrane transporter activity | sodium ion transmembrane transporter activity | secondary active transmembrane transporter activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | solute:sodium symporter activity

GO Biological Process

bile acid transmembrane transporter activity | establishment of localization | cellular process | monocarboxylic acid transport | localization | metal ion transport | anion transport | bile acid:sodium symporter activity | transmembrane transporter activity | organic cyclic compound metabolic process | oxoacid metabolic process | monocarboxylic acid metabolic process | transport | organic acid transmembrane transporter activity | symporter activity | lipid metabolic process | ion transmembrane transport | organic substance transport | sodium ion transport | cation transmembrane transporter activity | monovalent inorganic cation transport | active transmembrane transporter activity | small molecule metabolic process | transporter activity | organic acid transport | ion transmembrane transporter activity | solute:cation symporter activity | cellular ketone metabolic process | organic acid:sodium symporter activity | organic anion transport | substrate-specific transmembrane transporter activity | carboxylic acid transmembrane transporter activity | carboxylic acid metabolic process | bile acid metabolic process | metal ion transmembrane transporter activity | metabolic process | primary metabolic process | bile acid and bile salt transport | sodium ion transmembrane transport | organic substance metabolic process | monocarboxylic acid transmembrane transporter activity | sodium ion transmembrane transporter activity | secondary active transmembrane transporter activity | substrate-specific transporter activity | steroid metabolic process | transmembrane transport | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | organic acid metabolic process | carboxylic acid transport | cation transport | ion transport | cellular metabolic process | solute:sodium symporter activity

GO Cellular Component

integral to membrane | plasma membrane part | cell | intrinsic to membrane | plasma membrane | membrane part | integral to plasma membrane | cell part | cell periphery | basolateral plasma membrane | membrane | intrinsic to plasma membrane