Clear Search sequence regions
Bookmark Forward

QuickView for Pivmecillinam (compound)


PubChem
Name: Amdinocillin Pivoxil
PubChem Compound ID: 115162
Description: Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.
Molecular formula: C21H34ClN3O5S
Molecular weight: 476.031 g/mol
Synonyms:
Melysin; EINECS 251-278-7; Pivmecillinam hydrochloride (JP15); Pivmecilinamo clorhidrato [Spanish]; Selexid; FL-1039; D01499; Melysin (TN); 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (2S,5R,6R)-; 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(((hexahydro-1H-azepin-1-yl)methylene)amino)-3,3-dimethyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (2S-(2alpha,5alpha,6beta))-.
show more »
DrugBank
Identification
Name: Amdinocillin Pivoxil
Name (isomeric): DB01605
Drug Type: small molecule
Description: Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.
Synonyms:
Amdinocillin pivoxil; Pivmecillinamum [inn-latin]; Pivmecilinamo [inn-spanish]
Brand: Selexid, Coactabs
Category: Anti-Bacterial Agents, Penicillins, Anti-Infective Agents, Urinary
CAS number: 32886-97-8
Pharmacology
Indication: Used to treat infections due to mecillinam-sensitive organisms such as urinary tract infections, salmonellosis and typhoid fever.
Pharmacology: Pivmecillinam is a pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdinocillin.
Mechanism of Action: Pivmecillinam interferes with the biosynthesis of the bacterial cell wall however its activity is slightly different from that of other penicillins and cephalosporins
Absorption: Well absorbed following oral administration.
Affected organisms: Enteric bacteria and other eubacteria
Interactions
Food interaction:
Take without regard to meals.
Drug interaction:
OxytetracyclinePossible antagonism of action
MethacyclinePossible antagonism of action
DoxycyclinePossible antagonism of action
DemeclocyclinePossible antagonism of action
RolitetracyclinePossible antagonism of action
show more »

Targets