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QuickView for NEUROG3 (gene)


Gene Symbol:
NEUROG3 Homo sapiens Homo sapiens
Full name:
neurogenin 3
Synonyms:
Atoh5, bHLHa7, class A basic helix-loop-helix protein 7, NGN-3, ngn3, neurogenin 3, neurogenin-3, OTTHUMP00000019730, Math4B, protein atonal homolog 5
Genomic Location:
Chr 10: 71001797-71003128
Description:
Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm (Gradwohl et al., 20...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 10
10q21.3


Transcripts Names
NM_020999
Protein Names
Q5VVI0
Q6DJX6
Q9BY24
Q9Y4Z2



GO Molecular Function

transcription factor binding transcription factor activity | nucleic acid binding | nucleic acid binding transcription factor activity | binding | structure-specific DNA binding | DNA binding | organic cyclic compound binding | transcription coactivator activity | protein binding | double-stranded DNA binding | sequence-specific DNA binding transcription factor activity | protein dimerization activity | protein binding transcription factor activity | transcription cofactor activity | heterocyclic compound binding

GO Biological Process

RNA metabolic process | regulation of biological process | transcription factor binding transcription factor activity | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | regulation of cell development | regulation of biosynthetic process | positive regulation of sequence-specific DNA binding transcription factor activity | nucleic acid metabolic process | positive regulation of developmental process | cell differentiation | cellular macromolecule metabolic process | nervous system development | neurogenesis | generation of neurons | positive regulation of cellular biosynthetic process | cellular process | peripheral nervous system development | positive regulation of nitrogen compound metabolic process | regulation of nucleobase-containing compound metabolic process | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | endocrine pancreas development | nucleic acid binding transcription factor activity | regulation of macromolecule biosynthetic process | positive regulation of nucleobase-containing compound metabolic process | macromolecule biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | system development | nitrogen compound metabolic process | multicellular organismal development | positive regulation of RNA metabolic process | regulation of neuron differentiation | regulation of gene expression | pancreas development | positive regulation of cellular metabolic process | regulation of multicellular organismal development | regulation of macromolecule metabolic process | regulation of nitrogen compound metabolic process | single-organism process | regulation of transcription from RNA polymerase II promoter | positive regulation of cell differentiation | biological regulation | biosynthetic process | regulation of primary metabolic process | positive regulation of macromolecule metabolic process | endocrine system development | positive regulation of biological process | regulation of cellular macromolecule biosynthetic process | regulation of cellular metabolic process | positive regulation of biosynthetic process | transcription coactivator activity | regulation of RNA metabolic process | positive regulation of molecular function | sequence-specific DNA binding transcription factor activity | cellular developmental process | regulation of cellular biosynthetic process | regulation of sequence-specific DNA binding transcription factor activity | anatomical structure development | regulation of multicellular organismal process | metabolic process | primary metabolic process | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organ development | gene expression | transcription, DNA-dependent | regulation of transcription, DNA-dependent | regulation of molecular function | protein binding transcription factor activity | cellular macromolecule biosynthetic process | regulation of nervous system development | regulation of developmental process | developmental process | positive regulation of cellular process | positive regulation of transcription, DNA-dependent | transcription cofactor activity | epithelial cell differentiation | single-multicellular organism process | positive regulation of transcription from RNA polymerase II promoter | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | positive regulation of neuron differentiation | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | cell part | membrane-bounded organelle | nucleus | organelle | intracellular part | intracellular