Clear Search sequence regions
Bookmark Forward

QuickView for Mestranol (compound)


PubChem
Name: Mestranol
PubChem Compound ID: 4080
Description: The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONTRACEPTIVES.
Molecular formula: C21H26O2
Molecular weight: 310.43 g/mol
Synonyms:
SC 4725; 17.alpha.-Ethinylestradiol 3-methyl ether; Ethynyloestradiol 3-methyl ether; EE3ME; Inostral; 3-Methoxy-17.alpha.-ethynyl-1,3,5(10)-oestratrien-17.beta.-ol; Ethinyloestradiol 3-methyl ether; 3-Methoxy-17.alpha.-ethynyl-1,3,5(10)-estratrien-17.beta.-ol; 17.alpha.-Ethynyl-3-methoxy-17.beta.-hydroxy-.delta.-1,3, 5(10)-estratriene; Component of Enovid.
show more »
DrugBank
Identification
Name: Mestranol
Name (isomeric): DB01357
Drug Type: small molecule
Description: The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONTRACEPTIVES.
Category: Estrogens
CAS number: 72-33-3
Pharmacology
Indication: Mestranol was used as one of the first oral contraceptives.
Mechanism of Action:
Mestranol is the 3-methyl ether of ethinylestradiol. Ethinylestradiol, is a synthetic derivative of estradiol. Ethinylestradiol is orally bio-active and the estrogen used in almost all modern formulations of combined oral contraceptive pills. It binds to (and activates) the estrogen receptor. Mestranol is a biologically inactive prodrug of ethinyl...
show more »
Interactions
Drug interaction:
DicloxacillinThis anti-infectious agent could decrease the effect of the oral contraceptive
CarbamazepineThis product may cause a slight decrease of contraceptive effect
TolbutamideTolbutamide, a strong CYP2C9 inhibitor, may decrease the metabolism and clearance of Mestranol. Consider alternate therapy or monitor for changes in Mestranol therapeutic and adverse effects if Tolbutamide is initiated, discontinued or dose changed.
Penicillin VThis anti-infectious agent could decrease the effect of the oral contraceptive
MinocyclineThis anti-infectious agent could decrease the effect of the oral contraceptive
show more »

Targets


Enzymes