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QuickView for KCNJ11 (gene)


Gene Symbol:
KCNJ11 Homo sapiens Homo sapiens
Full name:
potassium inwardly-rectifying channel, subfamily J, member 11
Synonyms:
inward rectifier K(+) channel Kir6.2, inwardly rectifying potassium channel KIR6.2, KIR6.2, IKATP, HHF2, potassium channel inwardly rectifing subfamily J member 11, potassium channel, inwardly rectifying subfamily J member 11, potassium inwardly-rectifying channel J11, potassium inwardly-rectifying channel, subfamily J, member 11, PHHI, MGC133230, TNDM3, beta-cell inward rectifier subunit, BIR, ATP-sensitive inward rectifier potassium channel 11
Genomic Location:
Chr 11: 17363371-17366782
Description:
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 11
11p15.1


Transcripts Names
NM_000525
NM_001166290
Protein Names
E9PNK0
B2RC52
B4DWI4



GO Molecular Function

ligand-gated channel activity | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | ribonucleotide binding | inward rectifier potassium channel activity | transmembrane transporter activity | ligand-gated ion channel activity | nucleotide binding | potassium ion binding | binding | ion channel binding | ATP binding | cytoskeletal protein binding | adenyl nucleotide binding | cation transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | gated channel activity | substrate-specific transmembrane transporter activity | ion binding | ankyrin binding | organic cyclic compound binding | voltage-gated potassium channel activity | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | potassium channel activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | cation channel activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | monovalent inorganic cation transmembrane transporter activity | voltage-gated channel activity | adenyl ribonucleotide binding | channel activity | alkali metal ion binding | ATP-activated inward rectifier potassium channel activity | metal ion binding | ion channel activity | heterocyclic compound binding | substrate-specific channel activity | small molecule binding

GO Biological Process

regulation of biological process | response to ATP | regulation of cellular localization | negative regulation of peptide secretion | regulation of localization | establishment of localization | regulation of biological quality | negative regulation of cellular process | glucose metabolic process | ligand-gated channel activity | response to drug | generation of precursor metabolites and energy | cellular chemical homeostasis | voltage-gated ion channel activity | regulation of peptide hormone secretion | multicellular organismal signaling | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | synaptic transmission | negative regulation of secretion | negative regulation of hormone secretion | regulation of cellular process | inward rectifier potassium channel activity | transmembrane transporter activity | ligand-gated ion channel activity | regulation of peptide secretion | response to stimulus | regulation of transmembrane transport | response to chemical stimulus | transport | regulation of insulin secretion | negative regulation of transport | regulation of peptide transport | cell-cell signaling | regulation of membrane potential | potassium ion import | ion transmembrane transport | regulation of hormone secretion | neurological system process | cation transmembrane transporter activity | cellular ion homeostasis | monovalent inorganic cation transport | single-organism process | monosaccharide metabolic process | small molecule metabolic process | transporter activity | cellular potassium ion transport | ion transmembrane transporter activity | potassium ion transport | gated channel activity | biological regulation | negative regulation of peptide hormone secretion | carbohydrate metabolic process | substrate-specific transmembrane transporter activity | cell communication | voltage-gated potassium channel activity | system process | homeostatic process | potassium channel activity | response to organic substance | metal ion transmembrane transporter activity | voltage-gated cation channel activity | potassium ion transmembrane transporter activity | metabolic process | primary metabolic process | hexose metabolic process | oxidation-reduction process | chemical homeostasis | regulation of secretion | ion homeostasis | regulation of ion transmembrane transport | negative regulation of biological process | cation channel activity | substrate-specific transporter activity | regulation of cell communication | transmembrane transport | negative regulation of insulin secretion | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | energy reserve metabolic process | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | energy derivation by oxidation of organic compounds | ATP-activated inward rectifier potassium channel activity | regulation of transport | potassium ion transmembrane transport | single-multicellular organism process | single organism signaling | transmission of nerve impulse | ion channel activity | ion transport | cellular metabolic process | substrate-specific channel activity | regulation of signaling | multicellular organismal process

GO Cellular Component

integral to membrane | sarcolemma | plasma membrane part | potassium channel complex | cell | intrinsic to membrane | ATP-sensitive potassium channel complex | macromolecular complex | plasma membrane | voltage-gated potassium channel complex | membrane part | integral to plasma membrane | T-tubule | cell part | cell periphery | cation channel complex | ion channel complex | membrane | protein complex | intrinsic to plasma membrane