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QuickView for GRIA2 (gene)


Gene Symbol:
GRIA2 Homo sapiens Homo sapiens
Full name:
glutamate receptor, ionotropic, AMPA 2
Synonyms:
AMPA-selective glutamate receptor 2, OTTHUMP00000165324, GluA2, GluR-2, gluR-B, GluR-K2, GLUR2, GLURB, glutamate receptor 2, glutamate receptor, ionotropic, AMPA 2, HBGR2
Genomic Location:
Chr 4: 158361186-158506677
Description:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated ca...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 4
4q32.1


Transcripts Names
NM_000826
NM_001083619
NM_001083620
Protein Names
P42262
Q96FP6



GO Molecular Function

kinase binding | ligand-gated channel activity | passive transmembrane transporter activity | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | transmembrane transporter activity | ligand-gated ion channel activity | binding | kainate selective glutamate receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | gated channel activity | alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | extracellular ligand-gated ion channel activity | glutamate receptor activity | substrate-specific transmembrane transporter activity | receptor activity | molecular transducer activity | protein binding | ionotropic glutamate receptor activity | signal transducer activity | excitatory extracellular ligand-gated ion channel activity | extracellular-glutamate-gated ion channel activity | substrate-specific transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of biological process | establishment of localization | ligand-gated channel activity | multicellular organismal signaling | cellular process | localization | passive transmembrane transporter activity | synaptic transmission | transmembrane signaling receptor activity | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | response to chemical stimulus | transport | cell-cell signaling | ion transmembrane transport | neurological system process | kainate selective glutamate receptor activity | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity | biological regulation | extracellular ligand-gated ion channel activity | glutamate receptor activity | response to toxin | substrate-specific transmembrane transporter activity | cell communication | system process | ionotropic glutamate receptor activity | cell surface receptor signaling pathway | signal transducer activity | cellular response to stimulus | excitatory extracellular ligand-gated ion channel activity | extracellular-glutamate-gated ion channel activity | substrate-specific transporter activity | response to fungicide | transmembrane transport | signaling | channel activity | glutamate receptor signaling pathway | single-multicellular organism process | single organism signaling | transmission of nerve impulse | ion channel activity | ion transport | ionotropic glutamate receptor signaling pathway | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

presynaptic membrane | endoplasmic reticulum part | dendritic spine | integral to membrane | dendrite | intracellular membrane-bounded organelle | synapse | plasma membrane part | neuron projection | endocytic vesicle membrane | clathrin-coated vesicle membrane | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic to membrane | synaptic membrane | terminal button | intracellular non-membrane-bounded organelle | cell projection part | cytoplasm | dendrite cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | synapse part | nuclear outer membrane-endoplasmic reticulum membrane network | macromolecular complex | cell projection | postsynaptic membrane | endomembrane system | neuron spine | endoplasmic reticulum membrane | cell projection cytoplasm | plasma membrane | perikaryon | axon part | organelle part | intracellular organelle part | dendritic spine head | vesicle | postsynaptic density | asymmetric synapse | site of polarized growth | membrane part | integral to plasma membrane | synaptic vesicle | cell part | coated vesicle membrane | membrane-bounded organelle | dendritic shaft | organelle | vesicle membrane | axon terminus | cell periphery | cytoplasmic part | axon | cytoplasmic membrane-bounded vesicle | ionotropic glutamate receptor complex | cytoplasmic vesicle part | growth cone | neuron projection terminus | synaptic vesicle membrane | membrane-bounded vesicle | non-membrane-bounded organelle | cytoskeleton | intracellular part | endocytic vesicle | intracellular | cell junction | membrane | cytoskeletal part | cytoplasmic vesicle membrane | protein complex | alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex | intrinsic to plasma membrane | coated vesicle