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QuickView for GABRA5 (gene)


Gene Symbol:
GABRA5 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid (GABA) A receptor, alpha 5
Synonyms:
GABA(A) receptor subunit alpha-5, gamma-aminobutyric acid (GABA) A receptor, alpha 5, gamma-aminobutyric acid receptor subunit alpha-5, MGC138184
Genomic Location:
Chr 15: 24663151-24776749
Description:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcri...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 15
15q12





GO Molecular Function

anion transmembrane transporter activity | ligand-gated channel activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | chloride channel activity | inorganic anion transmembrane transporter activity | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | gated channel activity | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | receptor activity | molecular transducer activity | signal transducer activity | anion channel activity | substrate-specific transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

brain development | regulation of biological process | behavioral fear response | establishment of localization | anion transmembrane transporter activity | cell differentiation | ligand-gated channel activity | defense response | nervous system development | neurogenesis | generation of neurons | sensory perception of mechanical stimulus | multicellular organismal signaling | cellular process | GABA-A receptor activity | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | synaptic transmission | neuron development | anion transport | learning | transmembrane signaling receptor activity | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | associative learning | response to stimulus | transport | response to stress | chloride channel activity | chloride transport | inorganic anion transport | inner ear receptor cell differentiation | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | system development | multicellular organismal development | inner ear receptor cell development | chloride transmembrane transporter activity | learning or memory | ion transmembrane transport | mechanoreceptor differentiation | neurological system process | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | cognition | biological regulation | innervation | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | sensory organ development | GABA receptor activity | cell communication | sensory perception of sound | system process | inner ear development | neuron differentiation | multicellular organismal response to stress | fear response | cellular developmental process | anatomical structure development | cell surface receptor signaling pathway | signal transducer activity | anion channel activity | ear development | behavior | cellular response to stimulus | organ development | nerve development | substrate-specific transporter activity | sensory perception | transmembrane transport | signaling | cell development | single-organism behavior | channel activity | developmental process | behavioral defense response | cochlea development | single-multicellular organism process | single organism signaling | transmission of nerve impulse | central nervous system development | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral to membrane | dendrite | synapse | plasma membrane part | neuron projection | cell body | cell | neuronal cell body | intrinsic to membrane | synaptic membrane | synapse part | macromolecular complex | cell projection | postsynaptic membrane | plasma membrane | chloride channel complex | neuronal cell body membrane | membrane part | integral to plasma membrane | cell part | cell periphery | cell body membrane | ion channel complex | cell junction | membrane | protein complex | intrinsic to plasma membrane