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QuickView for GABRA4 (gene)


Gene Symbol:
GABRA4 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid (GABA) A receptor, alpha 4
Synonyms:
N/A
Genomic Location:
Chr 4: 46615674-46690337
Description:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provide...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4p12


Transcripts Names
NM_000809
NM_001204266
NM_001204267
Protein Names
P48169
Q8IYR7



GO Molecular Function

neurotransmitter receptor activity | anion transmembrane transporter activity | ligand-gated channel activity | benzodiazepine receptor activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | chloride channel activity | inorganic anion transmembrane transporter activity | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | gated channel activity | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | receptor activity | molecular transducer activity | signal transducer activity | anion channel activity | substrate-specific transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of biological process | neurotransmitter receptor activity | establishment of localization | anion transmembrane transporter activity | ligand-gated channel activity | nervous system development | benzodiazepine receptor activity | multicellular organismal signaling | regulation of response to stimulus | cellular process | GABA-A receptor activity | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | synaptic transmission | anion transport | transmembrane signaling receptor activity | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | transport | regulation of response to drug | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | system development | multicellular organismal development | chloride transmembrane transporter activity | ion transmembrane transport | neurological system process | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | biological regulation | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | cell communication | system process | anatomical structure development | cell surface receptor signaling pathway | signal transducer activity | anion channel activity | cellular response to stimulus | substrate-specific transporter activity | transmembrane transport | signaling | channel activity | developmental process | single-multicellular organism process | single organism signaling | transmission of nerve impulse | central nervous system development | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral to membrane | synapse | plasma membrane part | cell | intrinsic to membrane | synaptic membrane | synapse part | macromolecular complex | postsynaptic membrane | plasma membrane | chloride channel complex | membrane part | integral to plasma membrane | cell part | cell periphery | ion channel complex | cell junction | membrane | protein complex | intrinsic to plasma membrane