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QuickView for GABRA2 (gene)


Gene Symbol:
GABRA2 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid (GABA) A receptor, alpha 2
Synonyms:
OTTHUMP00000125269, GABA(A) receptor subunit alpha-2, GABA(A) receptor, alpha 2, gamma-aminobutyric acid (GABA) A receptor, alpha 2, gamma-aminobutyric acid A receptor, alpha 2, gamma-aminobutyric acid receptor subunit alpha-2, FLJ97076
Genomic Location:
Chr 4: 45946463-46086702
Description:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternat...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4p12


Transcripts Names
NM_000807
NM_001114175
Protein Names
P47869
Q59G14
A8K0U7



GO Molecular Function

neurotransmitter receptor activity | anion transmembrane transporter activity | ligand-gated channel activity | benzodiazepine receptor activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | chloride channel activity | inorganic anion transmembrane transporter activity | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | gated channel activity | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | receptor activity | molecular transducer activity | signal transducer activity | anion channel activity | substrate-specific transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of biological process | neurotransmitter receptor activity | establishment of localization | anion transmembrane transporter activity | regulation of biological quality | ligand-gated channel activity | benzodiazepine receptor activity | multicellular organismal signaling | cellular process | GABA-A receptor activity | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | synaptic transmission | anion transport | transmembrane signaling receptor activity | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | transport | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | regulation of neurotransmitter levels | chloride transmembrane transporter activity | ion transmembrane transport | neurological system process | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | biological regulation | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | cell communication | system process | cell surface receptor signaling pathway | signal transducer activity | anion channel activity | cellular response to stimulus | substrate-specific transporter activity | transmembrane transport | signaling | channel activity | neurotransmitter transport | single-multicellular organism process | single organism signaling | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral to organelle membrane | integral to membrane | intracellular membrane-bounded organelle | synapse | neuron projection | clathrin-coated vesicle membrane | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell | intrinsic to organelle membrane | intrinsic to membrane | synaptic membrane | cytoplasm | intracellular organelle | synapse part | macromolecular complex | cell projection | postsynaptic membrane | endomembrane system | plasma membrane | organelle part | intracellular organelle part | chloride channel complex | vesicle | membrane part | synaptic vesicle | cell part | coated vesicle membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | cytoplasmic part | axon | cytoplasmic membrane-bounded vesicle | cytoplasmic vesicle part | ion channel complex | synaptic vesicle membrane | membrane-bounded vesicle | intracellular part | integral to synaptic vesicle membrane | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | protein complex | coated vesicle