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QuickView for GABRA1 (gene)


Gene Symbol:
GABRA1 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid (GABA) A receptor, alpha 1
Synonyms:
GABA(A) receptor subunit alpha-1, GABA(A) receptor, alpha 1, gamma-aminobutyric acid (GABA) A receptor, alpha 1, gamma-aminobutyric acid receptor subunit alpha-1, ECA4, EJM, EJM5, OTTHUMP00000160870
Genomic Location:
Chr 5: 161206983-161258992
Description:
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors ar...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Unknown transcription factor binding site geneset 3 ELK1 binding site geneset 1 ETS1 binding site geneset 1 PCAF binding site geneset 1 YY1 binding site geneset 1 FOXA2 binding site geneset 1 JUN binding site geneset 2 STAT1 binding site geneset 1 AHR binding site geneset 2 EGR2 binding site geneset 1
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 5
5q34





GO Molecular Function

anion transmembrane transporter activity | ligand-gated channel activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | chloride channel activity | inorganic anion transmembrane transporter activity | binding | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | gated channel activity | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | receptor activity | molecular transducer activity | signal transducer activity | anion channel activity | substrate-specific transporter activity | channel activity | drug binding | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of biological process | establishment of localization | anion transmembrane transporter activity | ligand-gated channel activity | multicellular organismal signaling | cellular process | GABA-A receptor activity | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | synaptic transmission | anion transport | transmembrane signaling receptor activity | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | transport | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | chloride transmembrane transporter activity | ion transmembrane transport | neurological system process | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | biological regulation | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | GABA receptor activity | cell communication | system process | cell surface receptor signaling pathway | signal transducer activity | anion channel activity | cellular response to stimulus | neuron-neuron synaptic transmission | substrate-specific transporter activity | transmembrane transport | signaling | channel activity | synaptic transmission, GABAergic | single-multicellular organism process | single organism signaling | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral to membrane | synapse | plasma membrane part | cell | intrinsic to membrane | synaptic membrane | synapse part | macromolecular complex | postsynaptic membrane | plasma membrane | chloride channel complex | membrane part | integral to plasma membrane | cell part | cell periphery | ion channel complex | cell junction | membrane | protein complex | intrinsic to plasma membrane