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QuickView for FOXP1 (gene)


Gene Symbol:
FOXP1 Homo sapiens Homo sapiens
Full name:
forkhead box P1
Synonyms:
MGC12942, MGC88572, MGC99551, QRF1, FLJ23741, fork head-related protein like B, forkhead box P1, forkhead box protein P1, HSPC215, glutamine-rich factor 1, hFKH1B, 12CC4
Genomic Location:
Chr 3: 71087426-71715830
Description:
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gen...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Gallus gallus Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Unknown transcription factor binding site geneset 1 TCF3 binding site geneset 1 TFAP4 binding site geneset 1 MEF2A binding site geneset 1 PCAF binding site geneset 1 TAL1 binding site geneset 1 TAL1 binding site geneset 2 NHLH1 binding site geneset 2 TAL1 binding site geneset 3 Unknown transcription factor binding site geneset 13
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for miR-1 Predicted Gene Targets for miR-132 Predicted Gene Targets for miR-139 Predicted Gene Targets for miR-150 Predicted Gene Targets for miR-181 Predicted Gene Targets for miR-183 Predicted Gene Targets for miR-19 Predicted Gene Targets for miR-191 Predicted Gene Targets for miR-141 Predicted Gene Targets for miR-221
Cytogenetic Map:
chr 3
3p14.1





GO Molecular Function

sequence-specific DNA binding | sequence-specific DNA binding RNA polymerase II transcription factor activity | cation binding | nucleic acid binding | nucleic acid binding transcription factor activity | binding | chromatin binding | structure-specific DNA binding | DNA binding | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | DNA binding, bending | protein binding | protein homodimerization activity | zinc ion binding | double-stranded DNA binding | sequence-specific DNA binding transcription factor activity | transcription factor binding | protein dimerization activity | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | transition metal ion binding | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription from RNA polymerase II promoter | regulation of biological process | muscle tissue development | regulation of biosynthetic process | nucleic acid metabolic process | regulation of immune system process | negative regulation of cellular process | sequence-specific DNA binding RNA polymerase II transcription factor activity | cell differentiation | positive regulation of epithelial cell proliferation | cellular macromolecule metabolic process | B cell differentiation | pattern specification process | cellular process | regulation of epithelial cell proliferation involved in lung morphogenesis | lymphocyte differentiation | somatic diversification of immune receptors via germline recombination within a single locus | positive regulation of immune effector process | immune system development | regulation of nucleobase-containing compound metabolic process | negative regulation of cellular metabolic process | tissue development | muscle structure development | muscle cell differentiation | skeletal muscle organ development | regulation of cellular process | leukocyte activation | regulation of metabolic process | production of molecular mediator of immune response | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | pre-B cell differentiation | nucleic acid binding transcription factor activity | positive regulation of immune system process | positive regulation of immunoglobulin production | regulation of macromolecule biosynthetic process | skeletal muscle tissue development | regulation of cell proliferation | cardiac muscle tissue development | regulation of anatomical structure morphogenesis | macromolecule biosynthetic process | cardiovascular system development | cellular nitrogen compound metabolic process | negative regulation of metabolic process | hemopoiesis | cellular biosynthetic process | embryo development | DNA recombination | leukocyte differentiation | system development | nitrogen compound metabolic process | multicellular organismal development | negative regulation of RNA metabolic process | somatic recombination of immunoglobulin gene segments | regulation of gene expression | regulation of multicellular organismal development | regulation of macromolecule metabolic process | regulation of nitrogen compound metabolic process | single-organism process | negative regulation of nitrogen compound metabolic process | cardiac cell differentiation | regulation of transcription from RNA polymerase II promoter | positive regulation of production of molecular mediator of immune response | B cell activation | biological regulation | V(D)J recombination | biosynthetic process | regulation of primary metabolic process | immature B cell differentiation | positive regulation of biological process | regulation of cellular macromolecule biosynthetic process | negative regulation of nucleobase-containing compound metabolic process | striated muscle tissue development | regulation of cellular metabolic process | heart development | positive regulation of cell proliferation | regulation of RNA metabolic process | striated muscle cell differentiation | smooth muscle tissue development | lymphocyte activation | sequence-specific DNA binding transcription factor activity | cellular developmental process | regulation of cellular biosynthetic process | negative regulation of macromolecule biosynthetic process | DNA metabolic process | regulation of organ morphogenesis | regulation of sequence-specific DNA binding transcription factor activity | regulation of immune effector process | anatomical structure development | regulation of multicellular organismal process | metabolic process | primary metabolic process | immunoglobulin production | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-dependent | somatic diversification of immunoglobulins | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | organ development | gene expression | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity | negative regulation of biological process | transcription, DNA-dependent | cell activation | cardiac muscle cell differentiation | regulation of immunoglobulin production | regulation of transcription, DNA-dependent | negative regulation of macromolecule metabolic process | regulation of molecular function | regulation of epithelial cell proliferation | regulation of production of molecular mediator of immune response | somatic cell DNA recombination | cellular macromolecule biosynthetic process | somatic diversification of immune receptors | regulation of developmental process | regulation of mesenchymal cell proliferation | developmental process | negative regulation of cellular biosynthetic process | positive regulation of cellular process | positive regulation of mesenchymal cell proliferation | single-multicellular organism process | heterocycle metabolic process | negative regulation of cellular macromolecule biosynthetic process | immune system process | cellular metabolic process | hemopoietic or lymphoid organ development | circulatory system development | muscle organ development | immunoglobulin V(D)J recombination | positive regulation of epithelial cell proliferation involved in lung morphogenesis | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | nucleolus | intracellular non-membrane-bounded organelle | cytoplasm | intracellular organelle | macromolecular complex | nuclear part | nucleoplasm | organelle part | intracellular organelle part | organelle lumen | nucleoplasm part | cell part | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular organelle lumen | non-membrane-bounded organelle | intracellular part | intracellular | protein complex