Clear Search sequence regions
Bookmark Forward

QuickView for ERBB2 (gene)


Gene Symbol:
Erbb2 Rattus norvegicus Rattus norvegicus
Full name:
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Synonyms:
N/A
Genomic Location:
Chr 10: 87219157-87242919
Description:
may play a role in cell proliferation and differentiation [RGD]
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_017003
XM_003750918
XM_003752373
Protein Names
Q8K3F9



GO Molecular Function

transmembrane receptor protein tyrosine kinase activity | RNA polymerase binding | transmembrane signaling receptor activity | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | glycoprotein binding | growth factor binding | binding | catalytic activity | receptor signaling protein activity | ATP binding | small conjugating protein ligase binding | adenyl nucleotide binding | DNA binding | signaling receptor activity | purine nucleotide binding | RNA polymerase core enzyme binding | identical protein binding | transmembrane receptor protein kinase activity | protein heterodimerization activity | organic cyclic compound binding | nucleoside phosphate binding | receptor activity | molecular transducer activity | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | RNA polymerase I core binding | protein phosphatase binding | ubiquitin protein ligase binding | protein dimerization activity | signal transducer activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | Hsp90 protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | kinase activity | phosphatase binding | heat shock protein binding | heterocyclic compound binding | protein C-terminus binding | small molecule binding | receptor signaling protein tyrosine kinase activity

GO Biological Process

RNA metabolic process | negative regulation of leukocyte activation | regulation of ERK1 and ERK2 cascade | cell morphogenesis | regulation of biological process | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | positive regulation of Ras protein signal transduction | neuron projection morphogenesis | muscle tissue development | intracellular signal transduction | regulation of biosynthetic process | positive regulation of cell communication | regulation of programmed cell death | transmembrane receptor protein tyrosine kinase activity | regulation of transcription from RNA polymerase I promoter | nucleic acid metabolic process | response to hormone stimulus | regulation of immune system process | regulation of immature T cell proliferation in thymus | regulation of biological quality | negative regulation of cellular process | regulation of MAP kinase activity | cell differentiation | positive regulation of epithelial cell proliferation | regulation of T cell differentiation | cellular macromolecule metabolic process | striated muscle cell development | regulation of purine nucleotide catabolic process | nervous system development | response to drug | cellular chemical homeostasis | cell part morphogenesis | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | regulation of protein modification process | generation of neurons | multicellular organismal signaling | regulation of response to stimulus | positive regulation of GTPase activity | positive regulation of cellular biosynthetic process | cellular process | peripheral nervous system development | positive regulation of Ras GTPase activity | cellular homeostasis | axon ensheathment | cell projection morphogenesis | tissue remodeling | neuron development | response to progesterone stimulus | multicellular organismal reproductive process | positive regulation of protein kinase activity | negative regulation of apoptotic process | axon guidance | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | transmembrane signaling receptor activity | negative regulation of T cell proliferation | regulation of nucleobase-containing compound metabolic process | tissue development | regulation of transcription from RNA polymerase III promoter | regulation of cell differentiation | muscle structure development | muscle cell differentiation | skeletal muscle organ development | autonomic nervous system development | regulation of cellular process | cellular component organization or biogenesis | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | gliogenesis | hepaticobiliary system development | negative regulation of mononuclear cell proliferation | organic cyclic compound metabolic process | positive regulation of translation | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | mammary gland morphogenesis | response to stimulus | muscle cell development | cell morphogenesis involved in neuron differentiation | response to chemical stimulus | positive regulation of protein metabolic process | regulation of leukocyte activation | signal transduction by phosphorylation | positive regulation of phosphatidylinositol 3-kinase cascade | gland morphogenesis | response to stress | regulation of macromolecule biosynthetic process | negative regulation of lymphocyte activation | skeletal muscle tissue development | posttranscriptional regulation of gene expression | regulation of cell proliferation | positive regulation of nucleobase-containing compound metabolic process | ovulation cycle | ensheathment of neurons | phosphatidylinositol-mediated signaling | macromolecule biosynthetic process | positive regulation of transcription from RNA polymerase III promoter | reproduction | cardiovascular system development | rhythmic process | cellular nitrogen compound metabolic process | response to endogenous stimulus | positive regulation of protein serine/threonine kinase activity | regulation of action potential in neuron | protein modification process | negative regulation of immature T cell proliferation | regulation of cell adhesion | cellular biosynthetic process | macromolecule modification | muscle fiber development | catalytic activity | regulation of lymphocyte differentiation | tongue development | regulation of membrane potential | locomotion | receptor signaling protein activity | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | myelination | multicellular organismal development | positive regulation of RNA metabolic process | regulation of immature T cell proliferation | regulation of MAPK cascade | phosphorus metabolic process | mammary gland development | taxis | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | wound healing | regulation of T cell activation | regulation of small GTPase mediated signal transduction | regulation of gene expression | neurological system process | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of multicellular organismal development | regulation of lymphocyte activation | neuromuscular junction development | cellular ion homeostasis | response to axon injury | estrus | regulation of macromolecule metabolic process | liver development | regulation of transferase activity | signaling receptor activity | protein autophosphorylation | regulation of nitrogen compound metabolic process | single-organism process | negative regulation of T cell activation | enzyme linked receptor protein signaling pathway | positive regulation of intracellular protein kinase cascade | synapse organization | transmembrane receptor protein kinase activity | axonogenesis | positive regulation of hydrolase activity | regulation of lymphocyte proliferation | mammary gland involution | negative regulation of immature T cell proliferation in thymus | regulation of Rho protein signal transduction | biological regulation | biosynthetic process | regulation of primary metabolic process | regulation of cellular protein metabolic process | glial cell differentiation | phosphorylation | inositol lipid-mediated signaling | positive regulation of macromolecule metabolic process | regulation of GTPase activity | protein phosphorylation | cell morphogenesis involved in differentiation | regulation of cellular catabolic process | positive regulation of biological process | phosphate-containing compound metabolic process | sensory organ development | regulation of purine nucleotide metabolic process | ovulation cycle process | regulation of cellular macromolecule biosynthetic process | positive regulation of phosphorus metabolic process | striated muscle tissue development | regulation of nucleotide metabolic process | cell communication | positive regulation of transferase activity | regulation of cellular metabolic process | regulation of protein kinase activity | sympathetic nervous system development | negative regulation of cell activation | regulation of protein metabolic process | system process | positive regulation of signal transduction | positive regulation of biosynthetic process | heart development | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | striated muscle cell differentiation | regulation of microtubule-based process | regulation of catabolic process | protein tyrosine kinase activity | positive regulation of molecular function | neuron differentiation | multicellular organism reproduction | cellular component organization at cellular level | regulation of GTP catabolic process | protein metabolic process | positive regulation of protein modification process | regulation of growth | response to organic substance | gland development | estrous cycle phase | cellular developmental process | regulation of cellular biosynthetic process | regulation of kinase activity | response to wounding | regulation of intracellular protein kinase cascade | phosphatidylinositol 3-kinase cascade | anatomical structure development | regulation of multicellular organismal process | regulation of nucleotide catabolic process | cell surface receptor signaling pathway | positive regulation of small GTPase mediated signal transduction | signal transducer activity | cell projection organization | metabolic process | transferase activity, transferring phosphorus-containing groups | primary metabolic process | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | negative regulation of programmed cell death | phosphotransferase activity, alcohol group as acceptor | chemical homeostasis | positive regulation of Rho GTPase activity | cellular response to stimulus | nucleobase-containing compound metabolic process | single organism reproductive process | protein kinase activity | neuron projection development | organic substance metabolic process | regulation of hydrolase activity | cellular component morphogenesis | organ development | gene expression | regulation of cell activation | positive regulation of transcription from RNA polymerase I promoter | positive regulation of kinase activity | transferase activity | ion homeostasis | regulation of phosphate metabolic process | regulation of nucleoside metabolic process | negative regulation of biological process | transcription, DNA-dependent | positive regulation of MAPK cascade | anatomical structure formation involved in morphogenesis | regulation of cell communication | regulation of action potential | signaling | positive regulation of growth | regulation of transcription, DNA-dependent | cell development | regulation of T cell proliferation | regulation of molecular function | regulation of epithelial cell proliferation | cellular component organization or biogenesis at cellular level | regulation of T cell differentiation in thymus | positive regulation of phosphorylation | cellular protein metabolic process | regulation of Ras protein signal transduction | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of response to stimulus | positive regulation of MAP kinase activity | regulation of Ras GTPase activity | regulation of developmental process | kinase activity | developmental process | response to external stimulus | regulation of cell growth | cellular protein modification process | regulation of leukocyte proliferation | positive regulation of cellular process | positive regulation of transcription, DNA-dependent | negative regulation of cell proliferation | regulation of Rho GTPase activity | single-multicellular organism process | single organism signaling | heterocycle metabolic process | transmission of nerve impulse | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | regulation of mononuclear cell proliferation | negative regulation of lymphocyte proliferation | cellular metabolic process | regulation of cell death | response to steroid hormone stimulus | regulation of translation | negative regulation of cell death | circulatory system development | chemotaxis | motor neuron axon guidance | regulation of cellular component organization | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | regulation of phosphatidylinositol 3-kinase cascade | receptor signaling protein tyrosine kinase activity | positive regulation of gene expression | skeletal muscle fiber development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral to membrane | basal plasma membrane | intracellular membrane-bounded organelle | synapse | plasma membrane part | apical plasma membrane | endosomal part | organelle membrane | basal part of cell | cell | intrinsic to membrane | synaptic membrane | cytoplasm | intracellular organelle | receptor complex | apical part of cell | endosome membrane | synapse part | macromolecular complex | cell projection | postsynaptic membrane | plasma membrane | organelle part | intracellular organelle part | lateral loop | membrane raft | perinuclear region of cytoplasm | membrane part | cell part | endosome | microvillus | membrane-bounded organelle | nucleus | organelle | cell periphery | cytoplasmic part | basolateral plasma membrane | intracellular part | intracellular | myelin sheath | membrane | protein complex