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PubChem
Name: Calcium
PubChem Compound ID: 271
Description: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Molecular formula: Ca+2
Molecular weight: 40.078 g/mol
Synonyms:
Calcium 2+ Cation; [45]Ca2+; Calcosan (chloride); Calcium dication; Calcium ++ Counter Ion; Calcium(2+)ions; Calcium 2+ Ion; AIDS-003239; 139468-93-2; Calcium-Ion (Primary Site).
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DrugBank
Identification
Name: Calcium
Name (isomeric): DB01373
Drug Type: small molecule
Description: A basic element found in nearly all organized tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Pharmacology
Indication: Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. It is vital in cell signaling, muscular contractions, bone health, and signalling cascades.
Pharmacology:
Calcium (Ca2+) plays a pivotal role in the physiology and biochemistry of organisms and the cell. It plays an important role in signal transduction pathways, where it acts as a second messenger, in neurotransmitter release from neurons, contraction of all muscle cell types, and fertilization. Many enzymes require calcium ions as a cofactor, those o...
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Mechanism of Action:
Calcium plays a vital role in the anatomy, physiology and biochemistry of organisms and of the cell, particularly in signal transduction pathways. More than 500 human proteins are known to bind or transport calcium. The skeleton acts as a major mineral storage site for the element and releases Ca2+ ions into the bloodstream under controlled condi...
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Route of elimination: The kidney excretes 250 mmol a day in urine, and resorbs 245 mmol, leading to a net loss in the urine of 5 mmol/d.
Interactions
Drug interaction:
ClodronateFormation of non-absorbable complexes
AtazanavirThis gastric pH modifier decreases the levels/effects of atazanavir
PefloxacinFormation of non-absorbable complexes
DelavirdineThe antiacid decreases the effect of delavirdine
OfloxacinFormation of non-absorbable complexes
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Targets