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QuickView for CYP3A7 (gene)


Gene Symbol:
CYP3A7 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 3, subfamily A, polypeptide 7
Synonyms:
CYPIIIA7, cytochrome P450 3A7, cytochrome P450, family 3, subfamily A, polypeptide 7, cytochrome P450, subfamily IIIA, polypeptide 7, cytochrome P450-HFLA, CP37, aryl hydrocarbon hydroxylase, P450-HFLA, microsomal monooxygenase, flavoprotein-linked monooxygenase, xenobiotic monooxygenase
Genomic Location:
Chr 7: 99140596-99170757
Description:
This gene, CYP3A7, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the fo...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 7
7q21-q22.1


Transcripts Names
NM_000765
Protein Names
P24462
A4D288



GO Molecular Function

cation binding | iron ion binding | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

cellular process | cellular response to chemical stimulus | xenobiotic metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | small molecule metabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | metabolic process | oxidation-reduction process | cellular response to stimulus | cellular metabolic process | oxidoreductase activity | aromatase activity

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane