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QuickView for CYP3A5 (gene)


Gene Symbol:
CYP3A5 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 3, subfamily A, polypeptide 5
Synonyms:
flavoprotein-linked monooxygenase, niphedipine oxidase, microsomal monooxygenase, P450PCN3, PCN3, CP35, CYPIIIA5, cytochrome P-450, cytochrome P450 3A5, cytochrome P450 HLp2, cytochrome P450, family 3, subfamily A, polypeptide 5, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5, cytochrome P450-PCN3, aryl hydrocarbon hydroxylase, xenobiotic monooxygenase
Genomic Location:
Chr 7: 99083753-99115557
Description:
This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and ...
Orthologs:
Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes
External Links:
Entrez Gene
Cytogenetic Map:
chr 7
7q21.1





GO Molecular Function

cation binding | iron ion binding | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

cellular process | alkaloid metabolic process | cellular response to chemical stimulus | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | cellular nitrogen compound metabolic process | cellular catabolic process | drug catabolic process | catalytic activity | alkaloid catabolic process | nitrogen compound metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | small molecule metabolic process | response to xenobiotic stimulus | oxidative demethylation | cellular nitrogen compound catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | drug metabolic process | metabolic process | primary metabolic process | oxidation-reduction process | cellular response to stimulus | organic substance metabolic process | steroid metabolic process | demethylation | cellular metabolic process | oxidoreductase activity | aromatase activity

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane