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QuickView for CYP2C19 (gene)


Gene Symbol:
CYP2C19 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 2, subfamily C, polypeptide 19
Synonyms:
CYP 2C, CYP2C, CYPIIC17, CYPIIC19, cytochrome P-450 II C, cytochrome P450 2C19, cytochrome P450, family 2, subfamily C, polypeptide 19, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19, cytochrome P450-11A, cytochrome P450-254C, CPCJ, (R)-limonene 6-monooxygenase, (S)-limonene 6-monooxygenase, (S)-limonene 7-monooxygenase, flavoprotein-linked monooxygenase, xenobiotic monooxygenase, RP11-400G3.4, S-mephenytoin 4-hydroxylase, P450C2C, P450IIC19, microsomal monooxygenase, mephenytoin 4'-hydroxylase, mephenytoin 4-hydroxylase, OTTHUMP00000059588, OTTHUMP00000020132
Genomic Location:
Chr 10: 96512453-96602661
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the an...
Orthologs:
Mus musculus Rattus norvegicus Canis lupus familiaris
External Links:
Entrez Gene
Cytogenetic Map:
chr 10
10q24


Transcripts Names
NM_000769
Protein Names
Q9UCD4
P33261
P33259
Q8WZB2
Q8WZB1



GO Molecular Function

(S)-limonene 6-monooxygenase activity | cation binding | (S)-limonene 7-monooxygenase activity | enzyme binding | steroid hydroxylase activity | iron ion binding | limonene monooxygenase activity | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | ion binding | organic cyclic compound binding | tetrapyrrole binding | oxygen binding | protein binding | transition metal ion binding | heme binding | (R)-limonene 6-monooxygenase activity | metal ion binding | heterocyclic compound binding | oxidoreductase activity

GO Biological Process

molting cycle | (S)-limonene 6-monooxygenase activity | response to drug | cellular process | exogen | (S)-limonene 7-monooxygenase activity | cellular response to chemical stimulus | tissue development | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | organic cyclic compound metabolic process | cellular lipid metabolic process | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | limonene monooxygenase activity | hair follicle maturation | cellular catabolic process | drug catabolic process | catalytic activity | system development | multicellular organismal development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | lipid metabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen | single-organism process | small molecule metabolic process | exogenous drug catabolic process | terpenoid metabolic process | epidermis development | response to xenobiotic stimulus | molting cycle process | anatomical structure maturation | drug metabolic process | monoterpenoid metabolic process | hair cycle | anatomical structure development | metabolic process | primary metabolic process | developmental maturation | oxidation-reduction process | hair cycle process | cellular response to stimulus | organic substance metabolic process | organ development | steroid metabolic process | isoprenoid metabolic process | developmental process | (R)-limonene 6-monooxygenase activity | single-multicellular organism process | heterocycle metabolic process | cellular metabolic process | oxidoreductase activity | hair follicle development | multicellular organismal process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane