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QuickView for CYP2C18 (gene)


Gene Symbol:
CYP2C18 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 2, subfamily C, polypeptide 18
Synonyms:
cytochrome P450 2C18, cytochrome P450 family 2 subfamily C polypeptide 18, cytochrome P450, family 2, subfamily C, polypeptide 18, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18, cytochrome P450-6B/29C, CYP2C, CYP2C17, CYPIIC18, DKFZp686I24235, (S)-mephenytoin hydroxylase associated cytochrome P450, CPCI, flavoprotein-linked monooxygenase, RP11-466J14.4, unspecific monooxygenase, microsomal monooxygenase, P450-6B/29C, P450IIC17, OTTHUMP00000020131
Genomic Location:
Chr 10: 96433368-96485514
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The g...
Orthologs:
Mus musculus Rattus norvegicus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 10
10q24


Transcripts Names
NM_000772
NM_001128925



GO Molecular Function

cation binding | steroid hydroxylase activity | iron ion binding | binding | catalytic activity | testosterone 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | electron carrier activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | oxygen binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

cellular process | cellular response to chemical stimulus | xenobiotic metabolic process | steroid hydroxylase activity | response to stimulus | response to chemical stimulus | cellular response to xenobiotic stimulus | catalytic activity | testosterone 16-alpha-hydroxylase activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | small molecule metabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | metabolic process | oxidation-reduction process | cellular response to stimulus | cellular metabolic process | oxidoreductase activity | aromatase activity

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane