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QuickView for CYP1A2 (gene)


Gene Symbol:
CYP1A2 Homo sapiens Homo sapiens
Full name:
cytochrome P450, family 1, subfamily A, polypeptide 2
Synonyms:
flavoprotein-linked monooxygenase, aryl hydrocarbon hydroxylase, CYPIA2, dioxin-inducible P3-450, cytochrome P(3)450, cytochrome P450 1A2, cytochrome P450 4, cytochrome P450, family 1, subfamily A, polypeptide 2, cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2, cytochrome P450-P3, CP12, microsomal monooxygenase, P3-450, P450 form 4, P450(PA), xenobiotic monooxygenase
Genomic Location:
Chr 15: 72828237-72835994
Description:
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some pol...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 15
15q24.1


Transcripts Names
NM_000761
Protein Names
Q9UK49
Q16754
Q9BXX7
Q6NWU5
P05177



GO Molecular Function

cation binding | enzyme binding | iron ion binding | demethylase activity | binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor | electron carrier activity | oxidoreductase activity, acting on CH or CH2 groups | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | tetrapyrrole binding | protein binding | caffeine oxidase activity | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity

GO Biological Process

molting cycle | regulation of biological process | response to metal ion | respiratory tube development | response to drug | reactive oxygen species metabolic process | generation of precursor metabolites and energy | hydrogen peroxide biosynthetic process | cellular process | alkaloid metabolic process | toxin metabolic process | exogen | cellular respiration | cellular response to chemical stimulus | response to inorganic substance | tissue development | porphyrin-containing compound metabolic process | regulation of metabolic process | xenobiotic metabolic process | catabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular lipid metabolic process | cellular response to metal ion | response to stimulus | secondary metabolite biosynthetic process | oxoacid metabolic process | monocarboxylic acid metabolic process | response to chemical stimulus | respiratory system development | cellular response to xenobiotic stimulus | demethylase activity | hair follicle maturation | cellular response to inorganic substance | cellular response to cadmium ion | cofactor metabolic process | cellular biosynthetic process | cellular catabolic process | drug catabolic process | catalytic activity | system development | nitrogen compound metabolic process | multicellular organismal development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor | steroid catabolic process | lipid metabolic process | regulation of gene expression | methylation | regulation of macromolecule metabolic process | oxidoreductase activity, acting on CH or CH2 groups | dibenzo-p-dioxin metabolic process | single-organism process | small molecule metabolic process | oxidative deethylation | exogenous drug catabolic process | biological regulation | cellular ketone metabolic process | biosynthetic process | response to cadmium ion | terpenoid metabolic process | epidermis development | response to xenobiotic stimulus | molting cycle process | oxidative demethylation | post-embryonic development | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | anatomical structure maturation | organic cyclic compound catabolic process | drug metabolic process | carboxylic acid metabolic process | monoterpenoid metabolic process | caffeine oxidase activity | hair cycle | anatomical structure development | metabolic process | primary metabolic process | developmental maturation | oxidation-reduction process | hair cycle process | cellular response to stimulus | lipid catabolic process | organic substance metabolic process | organ development | secondary metabolic process | lung development | steroid metabolic process | organic acid metabolic process | isoprenoid metabolic process | energy derivation by oxidation of organic compounds | developmental process | tube development | single-multicellular organism process | toxin biosynthetic process | heterocycle metabolic process | demethylation | tetrapyrrole metabolic process | hydrogen peroxide metabolic process | cellular metabolic process | oxidoreductase activity | aromatase activity | hair follicle development | multicellular organismal process

GO Cellular Component

endoplasmic reticulum part | intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | organelle part | intracellular organelle part | membrane part | cell part | membrane-bounded organelle | organelle | cytoplasmic part | intracellular part | intracellular | membrane