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QuickView for CHRNA7 (gene)


Gene Symbol:
CHRNA7 Homo sapiens Homo sapiens
Full name:
cholinergic receptor, nicotinic, alpha 7 (neuronal)
Synonyms:
neuronal acetylcholine receptor protein, alpha-7 chain, neuronal acetylcholine receptor subunit alpha-7, NACHRA7, acetylcholine receptor, nicotinic, alpha 7 (neuronal), alpha 7 neuronal nicotinic acetylcholine receptor, alpha-7 nicotinic cholinergic receptor subunit, cholinergic receptor, nicotinic, alpha polypeptide 7, CHRNA7-2, cholinergic receptor, nicotinic, alpha 7, cholinergic receptor, nicotinic, alpha 7 (neuronal), a7 nicotinic acetylcholine receptor
Genomic Location:
Chr 15: 30110018-30248541
Description:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be hetero-pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N-terminal extracellular domain followed by three conserved ...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 15
15q14





GO Molecular Function

neurotransmitter receptor activity | ligand-gated channel activity | peptide binding | channel regulator activity | beta-amyloid binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | toxin binding | transmembrane transporter activity | ligand-gated ion channel activity | chloride channel regulator activity | binding | acetylcholine-activated cation-selective channel activity | cation transmembrane transporter activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | identical protein binding | ion transmembrane transporter activity | gated channel activity | extracellular ligand-gated ion channel activity | substrate-specific transmembrane transporter activity | acetylcholine binding | receptor activity | molecular transducer activity | protein binding | protein homodimerization activity | protein dimerization activity | signal transducer activity | excitatory extracellular ligand-gated ion channel activity | cation channel activity | substrate-specific transporter activity | channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of biological process | negative regulation of multicellular organismal process | neurotransmitter receptor activity | establishment of localization | regulation of biological quality | positive regulation of developmental process | regulation of MAP kinase activity | ligand-gated channel activity | cellular macromolecule metabolic process | cellular chemical homeostasis | positive regulation of phosphate metabolic process | regulation of protein modification process | multicellular organismal signaling | regulation of response to stimulus | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | synaptic transmission | positive regulation of protein kinase activity | response to hypoxia | positive regulation of catalytic activity | transmembrane signaling receptor activity | regulation of angiogenesis | regulation of cellular process | regulation of metabolic process | transmembrane transporter activity | negative regulation of tumor necrosis factor production | positive regulation of cellular protein metabolic process | ligand-gated ion channel activity | calcium ion homeostasis | regulation of vasculature development | response to stimulus | response to chemical stimulus | transport | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | regulation of anatomical structure morphogenesis | divalent metal ion transport | positive regulation of protein serine/threonine kinase activity | protein modification process | response to decreased oxygen levels | macromolecule modification | cell-cell signaling | activation of protein kinase activity | metal ion homeostasis | response to nicotine | response to oxygen levels | regulation of signal transduction | regulation of MAPK cascade | phosphorus metabolic process | acetylcholine-activated cation-selective channel activity | learning or memory | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | response to abiotic stimulus | neurological system process | cation transmembrane transporter activity | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of multicellular organismal development | cellular ion homeostasis | regulation of macromolecule metabolic process | acetylcholine receptor activity | regulation of transferase activity | signaling receptor activity | single-organism process | transporter activity | ion transmembrane transporter activity | gated channel activity | cognition | biological regulation | regulation of primary metabolic process | regulation of cellular protein metabolic process | extracellular ligand-gated ion channel activity | phosphorylation | positive regulation of macromolecule metabolic process | substrate-specific transmembrane transporter activity | protein phosphorylation | regulation of tumor necrosis factor production | cation homeostasis | positive regulation of biological process | phosphate-containing compound metabolic process | positive regulation of phosphorus metabolic process | cellular cation homeostasis | cell communication | positive regulation of transferase activity | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | system process | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | positive regulation of molecular function | activation of MAPK activity | protein metabolic process | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | regulation of intracellular protein kinase cascade | regulation of multicellular organismal process | signal transducer activity | metabolic process | primary metabolic process | chemical homeostasis | calcium ion transport | behavior | cellular response to stimulus | excitatory extracellular ligand-gated ion channel activity | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | negative regulation of biological process | cation channel activity | memory | substrate-specific transporter activity | regulation of cell communication | transmembrane transport | signaling | response to organic cyclic compound | single-organism behavior | regulation of molecular function | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | cation transport | channel activity | positive regulation of MAP kinase activity | cellular divalent inorganic cation homeostasis | regulation of developmental process | cellular protein modification process | positive regulation of cellular process | cellular metal ion homeostasis | single-multicellular organism process | single organism signaling | divalent inorganic cation transport | transmission of nerve impulse | ion channel activity | positive regulation of metabolic process | ion transport | cellular metabolic process | divalent inorganic cation homeostasis | substrate-specific channel activity | positive regulation of angiogenesis | signal transduction | regulation of signaling | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral to membrane | synapse | plasma membrane part | cell | intrinsic to membrane | synaptic membrane | receptor complex | synapse part | macromolecular complex | postsynaptic membrane | plasma membrane | membrane part | integral to plasma membrane | cell part | cell periphery | ion channel complex | cell junction | acetylcholine-gated channel complex | membrane | protein complex | intrinsic to plasma membrane