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QuickView for CACNB1 (gene)


Gene Symbol:
CACNB1 Homo sapiens Homo sapiens
Full name:
calcium channel, voltage-dependent, beta 1 subunit
Synonyms:
voltage-dependent L-type calcium channel subunit beta-1, OTTHUMP00000164286, MGC41896, CAB1, CACNLB1, calcium channel voltage-dependent subunit beta 1, calcium channel, L type, beta 1 polypeptide, calcium channel, voltage-dependent, beta 1 subunit, CCHLB1, dihydropyridine-sensitive L-type, calcium channel beta-1 subunit
Genomic Location:
Chr 17: 34583235-34607427
Description:
The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Unknown transcription factor binding site geneset 3 CEBPB binding site geneset 1 CEBPA binding site geneset 2 NF1 binding site geneset 2 PPARA binding site geneset 1 Unknown transcription factor binding site geneset 65 ITGAL binding site geneset 1 MYOG binding site geneset 2 SREBF1 binding site geneset 3 NF1 binding site geneset 3
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 17
17q21-q22





GO Molecular Function

high voltage-gated calcium channel activity | voltage-gated ion channel activity | passive transmembrane transporter activity | transmembrane transporter activity | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | gated channel activity | divalent inorganic cation transmembrane transporter activity | substrate-specific transmembrane transporter activity | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

cell morphogenesis | regulation of biological process | neuron projection morphogenesis | regulation of localization | high voltage-gated calcium channel activity | establishment of localization | cell differentiation | nervous system development | cell part morphogenesis | neurogenesis | voltage-gated ion channel activity | generation of neurons | intracellular transport | cellular process | localization | cell projection morphogenesis | protein transport | passive transmembrane transporter activity | metal ion transport | neuron development | macromolecule localization | axon guidance | establishment of localization in cell | regulation of cellular process | cellular component organization or biogenesis | transmembrane transporter activity | cellular component organization | response to stimulus | cell morphogenesis involved in neuron differentiation | regulation of transmembrane transport | response to chemical stimulus | transport | intracellular protein transport | cellular localization | divalent metal ion transport | voltage-gated calcium channel activity | locomotion | system development | multicellular organismal development | calcium ion transmembrane transport | taxis | ion transmembrane transport | cation transmembrane transporter activity | single-organism process | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | axonogenesis | gated channel activity | divalent inorganic cation transmembrane transporter activity | biological regulation | substrate-specific transmembrane transporter activity | cell morphogenesis involved in differentiation | neuron differentiation | cellular component organization at cellular level | cellular developmental process | metal ion transmembrane transporter activity | anatomical structure development | voltage-gated cation channel activity | cell projection organization | cellular protein localization | calcium ion transport | neuron projection development | cellular component morphogenesis | regulation of ion transmembrane transport | establishment of protein localization | cation channel activity | anatomical structure formation involved in morphogenesis | substrate-specific transporter activity | transmembrane transport | inorganic cation transmembrane transporter activity | cell development | protein localization | cellular component organization or biogenesis at cellular level | voltage-gated channel activity | anatomical structure morphogenesis | cation transport | cellular macromolecule localization | channel activity | regulation of ion transport | protein targeting to membrane | developmental process | response to external stimulus | calcium channel activity | regulation of transport | single-multicellular organism process | divalent inorganic cation transport | ion channel activity | protein targeting | ion transport | chemotaxis | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral to membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | sarcolemma | plasma membrane part | voltage-gated calcium channel complex | cell | intrinsic to membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | macromolecular complex | plasma membrane | membrane part | T-tubule | cell part | calcium channel complex | membrane-bounded organelle | organelle | sarcoplasm | cell periphery | cytoplasmic part | cation channel complex | ion channel complex | intracellular part | intracellular | membrane | protein complex