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QuickView for CACNA1B (gene)


Gene Symbol:
CACNA1B Homo sapiens Homo sapiens
Full name:
calcium channel, voltage-dependent, N type, alpha 1B subunit
Synonyms:
voltage-dependent N-type calcium channel subunit alpha-1B, voltage-gated calcium channel alpha subunit Cav2.2, voltage-gated calcium channel subunit alpha Cav2.2, BIII, brain calcium channel III, CACNL1A5, CACNN, calcium channel alpha12.2 subunit, calcium channel, L type, alpha-1 polypeptide, calcium channel, N type, calcium channel, voltage-dependent, alpha 1B subunit, N type, calcium channel, voltage-dependent, L type, alpha 1B subunit, calcium channel, voltage-dependent, N type, alpha 1B subunit, Cav2.2, Cav2.2 voltage-gated Ca2+ channel
Genomic Location:
Chr 9: 139892062-140136449
Description:
Voltage-dependent Ca(2+) channels are multisubunit complexes found in the membrane of many excitable cells that regulate calcium entry (see MIM 601011). N-type calcium channels, which control neurotransmitter release from neurons, are dihydropyridine-insensitive and omega-conotoxin-sensitive. The alpha-1 subunit forms the pore through which calcium...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 9
9q34


Transcripts Names
NM_000718
NM_001243812
Protein Names
Q00975
B1AQK5
B1AQK4



GO Molecular Function

voltage-gated ion channel activity | passive transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | binding | voltage-gated calcium channel activity | ATP binding | adenyl nucleotide binding | cation transmembrane transporter activity | purine nucleotide binding | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | gated channel activity | divalent inorganic cation transmembrane transporter activity | substrate-specific transmembrane transporter activity | organic cyclic compound binding | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | substrate-specific transporter activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | voltage-gated channel activity | adenyl ribonucleotide binding | channel activity | calcium channel activity | ion channel activity | heterocyclic compound binding | protein C-terminus binding | substrate-specific channel activity | small molecule binding

GO Biological Process

regulation of biological process | regulation of localization | establishment of localization | regulation of biological quality | cellular chemical homeostasis | voltage-gated ion channel activity | multicellular organismal signaling | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | synaptic transmission | regulation of cellular process | transmembrane transporter activity | regulation of transmembrane transport | transport | divalent metal ion transport | cell-cell signaling | regulation of membrane potential | voltage-gated calcium channel activity | calcium ion transmembrane transport | ion transmembrane transport | neurological system process | cation transmembrane transporter activity | cellular ion homeostasis | single-organism process | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | gated channel activity | divalent inorganic cation transmembrane transporter activity | biological regulation | substrate-specific transmembrane transporter activity | cell communication | system process | homeostatic process | metal ion transmembrane transporter activity | voltage-gated cation channel activity | chemical homeostasis | calcium ion transport | membrane depolarization | ion homeostasis | regulation of ion transmembrane transport | cation channel activity | substrate-specific transporter activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium channel activity | regulation of transport | single-multicellular organism process | single organism signaling | divalent inorganic cation transport | transmission of nerve impulse | ion channel activity | ion transport | substrate-specific channel activity | multicellular organismal process

GO Cellular Component

integral to membrane | plasma membrane part | voltage-gated calcium channel complex | cell | intrinsic to membrane | macromolecular complex | plasma membrane | membrane part | cell part | calcium channel complex | cell periphery | cation channel complex | ion channel complex | membrane | protein complex