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QuickView for Aprobarbital (compound)


PubChem
Name: allylpropymal
PubChem Compound ID: 6464
Molecular formula: C10H14N2O3
Molecular weight: 210.23 g/mol
Synonyms:
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)- (9CI); 5-Allyl-5-isopropylbarbituric acid sodium salt; Aprobarbital sodium; 125-88-2; Aprobarbital; Isonal (swedish); Sodium 5-allyl-5-isopropylbarbiturate; Alurate elixir verdum; Alurate; Isonal.
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DrugBank
Identification
Name: allylpropymal
Name (isomeric): DB01352
Drug Type: small molecule
CAS number: 77-02-1
Pharmacology
Mechanism of Action:
Aprobarbital (like all barbiturates) works by binding to the GABAA receptor at either the alpha or the beta sub unit. These are binding sites that are distinct from GABA itself and also distinct from the benzodiazepine binding site. Like benzodiazepines, barbiturates potentiate the effect of GABA at this receptor. This GABAA receptor binding decr...
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Interactions
Drug interaction:
FelodipineThe barbiturate, aprobarbital, decreases the effect of felodipine.
ClomifeneThe enzyme inducer, aprobarbital, decreases the effect of the hormone agent, clomifene.
DiethylstilbestrolThe enzyme inducer, aprobarbital, decreases the effect of the hormone agent, diethylstilbestrol.
QuinidineThe anticonvulsant, aprobarbital, decreases the effect of quinidine.
Ethinyl EstradiolThis product may cause a slight decrease of contraceptive effect
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Targets