Clear Search sequence regions
Bookmark Forward

QuickView for Amobarbital (compound)


PubChem
Name: Amobarbital
PubChem Compound ID: 2163
Description: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Molecular formula: C11H17N2O3-
Molecular weight: 225.264 g/mol
DrugBank
Identification
Name: Amobarbital
Name (isomeric): DB01351
Drug Type: small molecule
Description: A barbiturate with hypnotic and sedative properties (but not antianxiety). Adverse effects are mainly a consequence of dose-related CNS depression and the risk of dependence with continued use is high. (From Martindale, The Extra Pharmacopoeia, 30th ed, p565)
Brand: Isomytal
Category: GABA Modulators, Hypnotics and Sedatives
CAS number: 57-43-2
Pharmacology
Mechanism of Action:
Amobarbital (like all barbiturates) works by binding to the GABAA receptor at either the alpha or the beta sub unit. These are binding sites that are distinct from GABA itself and also distinct from the benzodiazepine binding site. Like benzodiazepines, barbiturates potentiate the effect of GABA at this receptor. This GABAA receptor binding decre...
show more »
Interactions
Drug interaction:
ClomifeneThe enzyme inducer, amobarbital, decreases the effect of the hormone agent, clomifene.
EstradiolThe enzyme inducer, amobarbital, decreases the effect of the hormone agent, estradiol.
DoxycyclineThe anticonvulsant, amobarbital, decreases the effect of doxycycline.
Ethinyl EstradiolThis product may cause a slight decrease of contraceptive effect
AminophyllineThe barbiturate, amobarbital, decreases the effect of aminophylline.
show more »

Targets


Enzymes