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QuickView for ABCG2 (gene)


Gene Symbol:
ABCG2 Homo sapiens Homo sapiens
Full name:
ATP-binding cassette, sub-family G (WHITE), member 2
Synonyms:
MRX, multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2, MXR, MXR1, placenta specific MDR protein, placenta-specific ATP-binding cassette transporter, MGC102821, mitoxantrone resistance protein, mitoxantrone resistance-associated protein, CDw338, ABC transporter, ATP-binding cassette sub-family G member 2, ATP-binding cassette transporter G2, ATP-binding cassette, sub-family G (WHITE), member 2, ATP-binding cassette, sub-family G, member 2, BCRP, BCRP1, BMDP, breast cancer resistance protein, CD338, ABC15, ABCP, UAQTL1, EST157481, GOUT1
Genomic Location:
Chr 4: 89230440-89299035
Description:
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the Whit...
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 4
4q22





GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | ATPase activity, coupled to movement of substances | xenobiotic transporter activity | drug transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | ATPase activity | pyrophosphatase activity | binding | catalytic activity | ATP binding | P-P-bond-hydrolysis-driven transmembrane transporter activity | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | identical protein binding | organic cyclic compound binding | drug transmembrane transporter activity | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | protein dimerization activity | primary active transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | heme transporter activity | cofactor transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | xenobiotic-transporting ATPase activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | purine nucleoside triphosphate metabolic process | nucleoside phosphate catabolic process | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | regulation of biological quality | response to drug | ATPase activity, coupled to movement of substances | xenobiotic transporter activity | organophosphate catabolic process | cellular chemical homeostasis | drug transporter activity | cellular process | localization | cellular homeostasis | nucleotide metabolic process | carbohydrate derivative catabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | purine-containing compound catabolic process | catabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | purine ribonucleoside triphosphate metabolic process | response to stimulus | purine nucleotide metabolic process | response to chemical stimulus | transport | heterocycle catabolic process | hydrolase activity | ATPase activity | cellular nitrogen compound metabolic process | pyrophosphatase activity | ribonucleotide catabolic process | cellular catabolic process | nucleobase-containing compound catabolic process | ribonucleoside triphosphate metabolic process | urate metabolic process | catalytic activity | metal ion homeostasis | nitrogen compound metabolic process | P-P-bond-hydrolysis-driven transmembrane transporter activity | nucleoside-triphosphatase activity | purine-containing compound metabolic process | organophosphate metabolic process | ATPase activity, coupled | cellular ion homeostasis | active transmembrane transporter activity | small molecule metabolic process | transporter activity | ATP catabolic process | nucleobase-containing small molecule metabolic process | biological regulation | purine nucleoside triphosphate catabolic process | purine ribonucleoside triphosphate catabolic process | nucleotide catabolic process | cation homeostasis | cellular cation homeostasis | drug transmembrane transporter activity | cellular nitrogen compound catabolic process | aromatic compound catabolic process | homeostatic process | iron ion homeostasis | organic cyclic compound catabolic process | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | nucleoside phosphate metabolic process | xenobiotic transport | cofactor transport | primary active transmembrane transporter activity | metabolic process | primary metabolic process | chemical homeostasis | hydrolase activity, acting on acid anhydrides | heme transporter activity | nucleobase-containing compound metabolic process | organic substance metabolic process | cofactor transporter activity | ion homeostasis | cellular iron ion homeostasis | drug transport | transmembrane transport | nucleoside triphosphate catabolic process | organic acid metabolic process | drug transmembrane transport | heme transport | xenobiotic-transporting ATPase activity | carbohydrate derivative metabolic process | cellular metal ion homeostasis | heterocycle metabolic process | purine ribonucleotide catabolic process | ribonucleoside triphosphate catabolic process | cellular metabolic process | ATP metabolic process | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | purine nucleotide catabolic process

GO Cellular Component

integral to membrane | cell | intrinsic to membrane | plasma membrane | membrane part | cell part | cell periphery | membrane