Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for ABCC4 (gene)


Gene Symbol:
ABCC4 Homo sapiens Homo sapiens
Full name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Synonyms:
OTTHUMP00000018560, MOAT-B, MOATB, MRP/cMOAT-related ABC transporter, MRP4, multi-specific organic anion transporter B, multidrug resistance-associated protein 4, multispecific organic anion transporter B, EST170205, RP11-74A12.1, canalicular multispecific organic anion transporter (ABC superfamily), bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4), ATP-binding cassette sub-family C member 4, ATP-binding cassette, sub-family C (CFTR/MRP), member 4, ATP-binding cassette, sub-family C, member 4
Genomic Location:
Chr 13: 94470084-94751688
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is i...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 13
13q32


Transcripts Names
NM_005845
NM_001105515



GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | ATPase activity, coupled to transmembrane movement of substances | ATPase activity, coupled to movement of substances | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | ATPase activity | pyrophosphatase activity | binding | catalytic activity | ATP binding | P-P-bond-hydrolysis-driven transmembrane transporter activity | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | organic cyclic compound binding | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | primary active transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | purine nucleoside triphosphate metabolic process | exocytosis | oxidoreductase activity, acting on CH-OH group of donors | nucleoside phosphate catabolic process | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | platelet degranulation | regulation of biological quality | ATPase activity, coupled to movement of substances | organophosphate catabolic process | cellular process | secretion | localization | nucleotide metabolic process | carbohydrate derivative catabolic process | hemostasis | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | purine-containing compound catabolic process | establishment of localization in cell | catabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | purine ribonucleoside triphosphate metabolic process | response to stimulus | purine nucleotide metabolic process | transport | heterocycle catabolic process | hydrolase activity | response to stress | cellular localization | secretion by cell | ATPase activity | cellular nitrogen compound metabolic process | pyrophosphatase activity | ribonucleotide catabolic process | cellular catabolic process | nucleobase-containing compound catabolic process | ribonucleoside triphosphate metabolic process | catalytic activity | blood coagulation | nitrogen compound metabolic process | P-P-bond-hydrolysis-driven transmembrane transporter activity | wound healing | platelet activation | nucleoside-triphosphatase activity | purine-containing compound metabolic process | organophosphate metabolic process | ATPase activity, coupled | single-organism process | active transmembrane transporter activity | small molecule metabolic process | vesicle-mediated transport | transporter activity | ATP catabolic process | nucleobase-containing small molecule metabolic process | biological regulation | purine nucleoside triphosphate catabolic process | purine ribonucleoside triphosphate catabolic process | nucleotide catabolic process | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity | cellular nitrogen compound catabolic process | aromatic compound catabolic process | organic cyclic compound catabolic process | coagulation | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | nucleoside phosphate metabolic process | response to wounding | primary active transmembrane transporter activity | metabolic process | primary metabolic process | regulation of body fluid levels | oxidation-reduction process | hydrolase activity, acting on acid anhydrides | nucleobase-containing compound metabolic process | organic substance metabolic process | cell activation | transmembrane transport | nucleoside triphosphate catabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | carbohydrate derivative metabolic process | single-multicellular organism process | heterocycle metabolic process | purine ribonucleotide catabolic process | ribonucleoside triphosphate catabolic process | cellular metabolic process | ATP metabolic process | oxidoreductase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | purine nucleotide catabolic process | multicellular organismal process

GO Cellular Component

secretory granule | integral to membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | platelet dense granule | intrinsic to membrane | cytoplasm | intracellular organelle | secretory granule membrane | endomembrane system | plasma membrane | organelle part | intracellular organelle part | vesicle | membrane part | cell part | membrane-bounded organelle | platelet dense granule membrane | organelle | vesicle membrane | cell periphery | cytoplasmic part | cytoplasmic membrane-bounded vesicle | cytoplasmic vesicle part | membrane-bounded vesicle | intracellular part | intracellular | membrane | cytoplasmic vesicle membrane