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QuickView for ABCC2 (gene)


Gene Symbol:
ABCC2 Homo sapiens Homo sapiens
Full name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms:
KIAA1010, DJS, canalicular multidrug resistance protein, canalicular multispecific organic anion transporter, canalicular multispecific organic anion transporter 1, ATP-binding cassette sub-family C member 2, ATP-binding cassette, sub-family C (CFTR/MRP), member 2, CMOAT, cMRP, ABC30, RP11-114F7.2, OTTHUMP00000020267, MRP2, multidrug resistance-associated protein 2
Genomic Location:
Chr 10: 101532493-101601571
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is i...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Gallus gallus Pan troglodytes Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 10
10q24


Transcripts Names
NM_000392



GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | anion transmembrane transporter activity | ATPase activity, coupled to movement of substances | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | ATPase activity | pyrophosphatase activity | binding | catalytic activity | ATP binding | P-P-bond-hydrolysis-driven transmembrane transporter activity | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | substrate-specific transmembrane transporter activity | organic cyclic compound binding | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | primary active transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | substrate-specific transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | purine nucleoside triphosphate metabolic process | nucleoside phosphate catabolic process | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | establishment of localization | anion transmembrane transporter activity | ATPase activity, coupled to movement of substances | organophosphate catabolic process | cellular process | localization | nucleotide metabolic process | carbohydrate derivative catabolic process | anion transport | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | purine-containing compound catabolic process | catabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | purine ribonucleoside triphosphate metabolic process | purine nucleotide metabolic process | transport | heterocycle catabolic process | hydrolase activity | ATPase activity | cellular nitrogen compound metabolic process | pyrophosphatase activity | ribonucleotide catabolic process | cellular catabolic process | nucleobase-containing compound catabolic process | ribonucleoside triphosphate metabolic process | catalytic activity | nitrogen compound metabolic process | P-P-bond-hydrolysis-driven transmembrane transporter activity | ion transmembrane transport | nucleoside-triphosphatase activity | purine-containing compound metabolic process | organophosphate metabolic process | ATPase activity, coupled | active transmembrane transporter activity | small molecule metabolic process | transporter activity | ATP catabolic process | ion transmembrane transporter activity | nucleobase-containing small molecule metabolic process | purine nucleoside triphosphate catabolic process | organic anion transport | purine ribonucleoside triphosphate catabolic process | nucleotide catabolic process | substrate-specific transmembrane transporter activity | cellular nitrogen compound catabolic process | aromatic compound catabolic process | organic cyclic compound catabolic process | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | nucleoside phosphate metabolic process | primary active transmembrane transporter activity | metabolic process | primary metabolic process | hydrolase activity, acting on acid anhydrides | nucleobase-containing compound metabolic process | organic substance metabolic process | substrate-specific transporter activity | transmembrane transport | nucleoside triphosphate catabolic process | carbohydrate derivative metabolic process | heterocycle metabolic process | purine ribonucleotide catabolic process | ion transport | ribonucleoside triphosphate catabolic process | cellular metabolic process | ATP metabolic process | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | purine nucleotide catabolic process

GO Cellular Component

integral to membrane | plasma membrane part | apical plasma membrane | cell | intrinsic to membrane | intercellular canaliculus | apical part of cell | cell-cell junction | plasma membrane | membrane part | integral to plasma membrane | cell part | cell periphery | cell junction | membrane | intrinsic to plasma membrane