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QuickView for ABCC1 (gene)


Gene Symbol:
ABCC1 Homo sapiens Homo sapiens
Full name:
ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Synonyms:
LTC4 transporter, leukotriene C(4) transporter, GS-X, DKFZp686N04233, DKFZp781G125, ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C, member 1, ABC29, ABCC, MRP, OTTHUMP00000045904, multidrug resistance protein, multidrug resistance-associated protein 1, multiple drug resistance protein 1, multiple drug resistance-associated protein, MRP1
Genomic Location:
Chr 16: 15950935-16144432
Description:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily wh...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Danio rerio Schizosaccharomyces pombe Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 16
16p13.1





GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | ATPase activity, coupled to movement of substances | xenobiotic transporter activity | drug transporter activity | ribonucleotide binding | transmembrane transporter activity | sphingolipid transporter activity | nucleotide binding | fatty acid transporter activity | hydrolase activity | organic acid transmembrane transporter activity | ATPase activity | pyrophosphatase activity | binding | catalytic activity | ATP binding | P-P-bond-hydrolysis-driven transmembrane transporter activity | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | substrate-specific transmembrane transporter activity | organic cyclic compound binding | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | glutathione S-conjugate-exporting ATPase activity | nucleoside phosphate binding | purine ribonucleoside triphosphate binding | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | primary active transmembrane transporter activity | long-chain fatty acid transporter activity | hydrolase activity, acting on acid anhydrides | modified amino acid transmembrane transporter activity | amino acid transmembrane transporter activity | substrate-specific transporter activity | lipid-transporting ATPase activity | glutathione transmembrane transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | efflux transmembrane transporter activity | glutathione S-conjugate-transporting ATPase activity | xenobiotic-transporting ATPase activity | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

purine ribonucleotide metabolic process | purine nucleoside triphosphate metabolic process | long-chain fatty acid transport | regulation of biological process | positive regulation of locomotion | plasma membrane long-chain fatty acid transport | cell motility | nucleoside phosphate catabolic process | regulation of localization | lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | oligopeptide transport | response to drug | ATPase activity, coupled to movement of substances | xenobiotic transporter activity | organophosphate catabolic process | positive regulation of cellular component movement | drug transporter activity | glutathione transmembrane transport | cellular process | monocarboxylic acid transport | regulation of cell motility | localization | nucleotide metabolic process | carbohydrate derivative catabolic process | macromolecule localization | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | purine-containing compound catabolic process | cellular response to chemical stimulus | regulation of cellular process | catabolic process | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | sphingolipid transporter activity | purine ribonucleoside triphosphate metabolic process | drug export | response to stimulus | purine nucleotide metabolic process | response to chemical stimulus | fatty acid transporter activity | transport | heterocycle catabolic process | hydrolase activity | response to stress | organic acid transmembrane transporter activity | ATPase activity | cellular nitrogen compound metabolic process | pyrophosphatase activity | ribonucleotide catabolic process | cellular catabolic process | nucleobase-containing compound catabolic process | ribonucleoside triphosphate metabolic process | cell chemotaxis | catalytic activity | locomotion | nitrogen compound metabolic process | cell migration | P-P-bond-hydrolysis-driven transmembrane transporter activity | taxis | fatty acid transport | nucleoside-triphosphatase activity | purine-containing compound metabolic process | organic substance transport | organophosphate metabolic process | ATPase activity, coupled | regulation of cell migration | active transmembrane transporter activity | small molecule metabolic process | peptide transport | transporter activity | ATP catabolic process | regulation of cellular component movement | response to oxidative stress | organic acid transport | nucleobase-containing small molecule metabolic process | positive regulation of cell migration | biological regulation | glutathione transport | cellular component movement | purine nucleoside triphosphate catabolic process | purine ribonucleoside triphosphate catabolic process | nucleotide catabolic process | substrate-specific transmembrane transporter activity | positive regulation of biological process | tripeptide transport | drug transmembrane transporter activity | carboxylic acid transmembrane transporter activity | cellular nitrogen compound catabolic process | glutathione S-conjugate-exporting ATPase activity | aromatic compound catabolic process | regulation of locomotion | organic cyclic compound catabolic process | amino acid transport | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | phospholipid transport | nucleoside phosphate metabolic process | modified amino acid transport | xenobiotic transport | amino acid transmembrane transport | phospholipid efflux | primary active transmembrane transporter activity | metabolic process | lipid localization | long-chain fatty acid transporter activity | primary metabolic process | hydrolase activity, acting on acid anhydrides | cellular response to stimulus | nucleobase-containing compound metabolic process | modified amino acid transmembrane transporter activity | organic substance metabolic process | amino acid transmembrane transporter activity | drug transport | substrate-specific transporter activity | lipid-transporting ATPase activity | transmembrane transport | glutathione transmembrane transporter activity | nucleoside triphosphate catabolic process | drug transmembrane transport | carboxylic acid transport | efflux transmembrane transporter activity | response to external stimulus | glutathione S-conjugate-transporting ATPase activity | localization of cell | xenobiotic-transporting ATPase activity | positive regulation of cellular process | carbohydrate derivative metabolic process | heterocycle metabolic process | lipid transporter activity | purine ribonucleotide catabolic process | ribonucleoside triphosphate catabolic process | cellular metabolic process | ATP metabolic process | positive regulation of cell motility | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | chemotaxis | purine nucleotide catabolic process

GO Cellular Component

integral to membrane | intracellular membrane-bounded organelle | plasma membrane part | cell | nuclear lumen | intrinsic to membrane | nucleolus | intracellular non-membrane-bounded organelle | cytoplasm | intracellular organelle | Golgi apparatus | nuclear part | plasma membrane | organelle part | intracellular organelle part | organelle lumen | membrane part | integral to plasma membrane | cell part | membrane-bounded organelle | nucleus | organelle | cell periphery | cytoplasmic part | membrane-enclosed lumen | basolateral plasma membrane | intracellular organelle lumen | non-membrane-bounded organelle | intracellular part | intracellular | membrane | intrinsic to plasma membrane