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Proteins that bind to single-stranded DNA (ssDNA) are essential for DNA replication, recombinational repair, and maintenance of genomic stability. Her…
Authors: Jun Huang, Zihua Gong, Gargi Ghosal, Junjie Chen
Source: Molecular cell. 2009 Aug 14
View Full TextHuman TopBP1 plays a critical role in the control of DNA replication checkpoint. In this study, we report a specific interaction between TopBP1 and BA…
Authors: Zihua Gong, Ja-Eun Kim, Charles Chung Yun Leung, J N Mark Glover, Junjie Chen
Source: Molecular cell. 2010 Feb 12
View Full TextHuman p66alpha and p66beta are two potent transcriptional repressors that interact with the methyl-CpG-binding domain proteins MBD2 and MBD3. An analy…
Authors: Zihua Gong, Marc Brackertz, Rainer Renkawitz
Source: Molecular and cellular biology. 2006 Jun
View Free Full TextThe Mi-2/NuRD complex is a multi-subunit protein complex with enzymatic activities involving chromatin remodeling and histone deacetylation. Targeting…
Authors: Marc Brackertz, Zihua Gong, Jörg Leers, Rainer Renkawitz
Source: Nucleic acids research. 2006
View Full TextGenomic stability in eukaryotic cells is maintained by the coordination of multiple cellular events including cell cycle checkpoint, DNA repair, trans…
Authors: Zihua Gong, Young-Wook Cho, Ja-Eun Kim, Kai Ge, Junjie Chen
Source: The Journal of biological chemistry. 2009 Mar 13
View Free Full TextBACKGROUND AND AIMS: Gut-origin bacterial translocation is one of the major causes of pancreatic necrotic tissue infection in patients with severe acu…
Authors: Xingpeng Wang, Zihua Gong, Kai Wu, Bingxian Wang, Yaozong Yuang
Source: Journal of gastroenterology and hepatology. 2003 Jan
View Full TextINTRODUCTION: Studies have revealed that emodin is a potent agent in the management of clinical and experimental acute pancreatitis, but the molecular…
Authors: Zihua Gong, Yaozog Yuan, Kaixian Lou, Shuiping Tu, Zukang Zhai, Jiayu Xu
Source: Pancreas. 2002 Aug
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