1 to 4 of 4 literature results

• Autophagy regulates lipid metabolism.

  The intracellular storage and utilization of lipids are critical to maintain cellular energy homeostasis. During nutrient deprivation, cellular lipids…

  Authors: Rajat Singh, Susmita Kaushik, Yongjun Wang, Youqing Xiang, Inna Novak, Masaaki Komatsu, Keiji Tanaka, Ana Maria Cuervo, Mark J Czaja

  Source: Nature. 2009 Apr 30

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• Differential effects of JNK1 and JNK2 inhibition on murine steatohepatitis and insulin resistance.

  Activation of c-Jun N-terminal kinase (JNK) has been implicated as a mechanism in the development of steatohepatitis. This finding, together with the …

  Authors: Rajat Singh, Yongjun Wang, Youqing Xiang, Kathryn E Tanaka, William A Gaarde, Mark J Czaja

  Source: Hepatology (Baltimore, Md.). 2009 Jan

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• Autophagy regulates adipose mass and differentiation in mice.

  The relative balance between the quantity of white and brown adipose tissue can profoundly affect lipid storage and whole-body energy homeostasis. How…

  Authors: Rajat Singh, Youqing Xiang, Yongjun Wang, Kiran Baikati, Ana Maria Cuervo, Yen K Luu, Yan Tang, Jeffrey E Pessin, Gary J Schwartz, Mark J Czaja

  Source: The Journal of clinical investigation. 2009 Nov

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• Loss of macroautophagy promotes or prevents fibroblast apoptosis depending on the death stimulus.

  Macroautophagy has been implicated as a mechanism of cell death. However, the relationship between this degradative pathway and cell death is unclear …

  Authors: Yongjun Wang, Rajat Singh, Ashish C Massey, Saul S Kane, Susmita Kaushik, Taneisha Grant, Youqing Xiang, Ana Maria Cuervo, Mark J Czaja

  Source: The Journal of biological chemistry. 2008 Feb 22

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