1 to 10 of 18 literature results

• A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking.

  Regulated exocytosis is essential for many biological processes and many components of the protein trafficking machinery are ubiquitous. However, ther…

  Authors: Young Ho Suh, Akira Terashima, Ronald S Petralia, Robert J Wenthold, John T R Isaac, Katherine W Roche, Paul A Roche

  Source: Nature neuroscience. 2010 Mar

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• Corequirement of PICK1 binding and PKC phosphorylation for stable surface expression of the metabotropic glutamate receptor mGluR7.

  The presynaptic metabotropic glutamate receptor (mGluR) mGluR7 modulates excitatory neurotransmission by regulating neurotransmitter release and plays…

  Authors: Young Ho Suh, Kenneth A Pelkey, Gabriela Lavezzari, Paul A Roche, Richard L Huganir, Chris J McBain, Katherine W Roche

  Source: Neuron. 2008 Jun 12

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• An essential role for PICK1 in NMDA receptor-dependent bidirectional synaptic plasticity.

  PICK1 is a calcium-sensing, PDZ domain-containing protein that interacts with GluR2 and GluR3 AMPA receptor (AMPAR) subunits and regulates their traff…

  Authors: Akira Terashima, Kenneth A Pelkey, Jong-Cheol Rah, Young Ho Suh, Katherine W Roche, Graham L Collingridge, Chris J McBain, John T R Isaac

  Source: Neuron. 2008 Mar 27

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• Crucial roles of neuronatin in insulin secretion and high glucose-induced apoptosis in pancreatic beta-cells.

  Neuronatin (Nnat) was initially identified as a selectively-expressed gene in neonatal brains, but its expression has been also identified in pancreat…

  Authors: Myung Kuk Joe, Hyo Jung Lee, Young Ho Suh, Kyu Lee Han, Joo Hyun Lim, Jihyun Song, Je Kyung Seong, Myeong Ho Jung

  Source: Cellular signalling. 2008 May

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• NFATc4 and ATF3 negatively regulate adiponectin gene expression in 3T3-L1 adipocytes.

  Expression of adiponectin decreases with obesity and insulin resistance. At present, the mechanisms responsible for negatively regulating adiponectin …

  Authors: Hyun Bae Kim, Minyoung Kong, Tae Min Kim, Young Ho Suh, Won-Ho Kim, Joo Hyun Lim, Ji Hyun Song, Myeong Ho Jung

  Source: Diabetes. 2006 May

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• AICAR potentiates ROS production induced by chronic high glucose: roles of AMPK in pancreatic beta-cell apoptosis.

  We previously demonstrated that chronic high glucose (33.3 mM) induced beta-cell dysfunction and apoptosis through glucokinase (GCK) downregulation, b…

  Authors: Won-Ho Kim, June Woo Lee, Young Ho Suh, Hyun Jung Lee, Seung Hee Lee, Yeo Kyoung Oh, Bin Gao, Myeong Ho Jung

  Source: Cellular signalling. 2007 Apr

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• Exposure to chronic high glucose induces beta-cell apoptosis through decreased interaction of glucokinase with mitochondria: downregulation of glucokinase in pancreatic beta-cells.

  Chronic hyperglycemia is toxic to pancreatic beta-cells, impairing cellular functioning as observed in type 2 diabetes; however, the mechanism underly…

  Authors: Won-Ho Kim, June Woo Lee, Young Ho Suh, Shin Hee Hong, Joo Sun Choi, Joo Hyun Lim, Ji Hyun Song, Bin Gao, Myeong Ho Jung

  Source: Diabetes. 2005 Sep

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• Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

  Insulin resistance occurs early in the disease process, preceding the development of type 2 diabetes. Therefore, the identification of molecules that …

  Authors: Young Ho Suh, Younyoung Kim, Jeong Hyun Bang, Kyoung Suk Choi, June Woo Lee, Won-Ho Kim, Tae Jeong Oh, Sungwhan An, Myeong Ho Jung

  Source: Journal of molecular endocrinology. 2005 Apr

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• Stable siRNA-mediated silencing of antizyme inhibitor: regulation of ornithine decarboxylase activity.

  Ornithine decarboxylase (ODC) is the rate-limiting enzyme involved in the biosynthesis of polyamines essential for cell growth and differentiation. Ab…

  Authors: Kyoung Suk Choi, Young Ho Suh, Won-Ho Kim, Tae Ho Lee, Myeong Ho Jung

  Source: Biochemical and biophysical research communications. 2005 Mar 4

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• Ectopic expression of Neuronatin potentiates adipogenesis through enhanced phosphorylation of cAMP-response element-binding protein in 3T3-L1 cells.

  Neuronatin (Nnat) is selectively expressed in the neonatal brain and is involved in neuronal differentiation during brain development. However, Nnat a…

  Authors: Young Ho Suh, Won Ho Kim, Changsuk Moon, Yun Hwa Hong, Su-Yong Eun, Joo Hyun Lim, Joo Sun Choi, Jihyun Song, Myeong Ho Jung

  Source: Biochemical and biophysical research communications. 2005 Nov 18

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