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Expression levels of estrogen receptor (ER) alpha govern estrogen-dependent growth, response to endocrine therapy, and prognosis in ERalpha-positive b…
Authors: Naoto Kondo, Tatsuya Toyama, Hiroshi Sugiura, Yoshitaka Fujii, Hiroko Yamashita
Source: Cancer research. 2008 Jul 1
View Full TextEndocrine therapy has become the most important treatment option for women with estrogen receptor (ER)-positive breast cancer. Urgently needed are pro…
Authors: Hiroko Yamashita, Mariko Nishio, Tatsuya Toyama, Hiroshi Sugiura, Naoto Kondo, Shunzo Kobayashi, Yoshitaka Fujii, Hirotaka Iwase
Source: Endocrine-related cancer. 2008 Sep
View Full TextIt is poorly understood how apoptotic signals arising from DNA damage are transmitted to mitochondria, which release apoptogenic factors into the cyto…
Authors: Akimitsu Konishi, Shigeomi Shimizu, Junko Hirota, Toshifumi Takao, Yuhong Fan, Yosuke Matsuoka, Lilin Zhang, Yoshihiro Yoneda, Yoshitaka Fujii, Arthur I Skoultchi,…
Source: Cell. 2003 Sep 19
View Full TextPostoperative nausea and vomiting (PONV) are distressing and frequent adverse events of anesthesia and surgery, with a relatively high incidence after…
Authors: Yoshitaka Fujii
Source: Current pharmaceutical design. 2005
View Full TextBACKGROUND: Pain on injection is a recognized adverse effect of propofol, an agent used to induce general anesthesia in surgical patients. Pretreatmen…
Authors: Yoshitaka Fujii, Michiyo Itakura
Source: Clinical therapeutics. 2009 Oct
View Full TextBACKGROUND: Pain on injection of propofol is a common clinical problem. Flurbiprofen axetil, an injectable prodrug of flurbiprofen, with or without ve…
Authors: Yoshitaka Fujii, Michiyo Itakura
Source: Clinical therapeutics. 2009 Apr
View Full TextSomatic alterations in cellular DNA underlie almost all human cancers. The prospect of targeted therapies and the development of high-resolution, geno…
Authors: Barbara A Weir, Michele S Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M Lin, Michael A Province, Aldi Kraja, Laura A Johnson,…
Source: Nature. 2007 Dec 6
View Free Full TextBACKGROUND: Breast cancer surgery performed with the patient under general anesthesia has been associated with a relatively high incidence of postoper…
Authors: Yoshitaka Fujii, Michiyo Itakura
Source: Clinical therapeutics. 2008 Nov
View Full TextBACKGROUND: Pain on injection is a recognized adverse event (AE) of propofol administration for the induction of general anesthesia. Pretreatment with…
Authors: Yoshitaka Fujii, Michiyo Itakura
Source: Clinical therapeutics. 2008 Feb
View Full TextBACKGROUND: Pain on injection is a recognized adverse event (AE) with propofol, an agent used to induce general anesthesia in surgical patients. Lidoc…
Authors: Yoshitaka Fujii, Masahiro Nakayama
Source: Clinical therapeutics. 2007 May
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