1 to 10 of 204 literature results

• miR-206 Expression is down-regulated in estrogen receptor alpha-positive human breast cancer.

  Expression levels of estrogen receptor (ER) alpha govern estrogen-dependent growth, response to endocrine therapy, and prognosis in ERalpha-positive b…

  Authors: Naoto Kondo, Tatsuya Toyama, Hiroshi Sugiura, Yoshitaka Fujii, Hiroko Yamashita

  Source: Cancer research. 2008 Jul 1

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• Low phosphorylation of estrogen receptor alpha (ERalpha) serine 118 and high phosphorylation of ERalpha serine 167 improve survival in ER-positive breast cancer.

  Endocrine therapy has become the most important treatment option for women with estrogen receptor (ER)-positive breast cancer. Urgently needed are pro…

  Authors: Hiroko Yamashita, Mariko Nishio, Tatsuya Toyama, Hiroshi Sugiura, Naoto Kondo, Shunzo Kobayashi, Yoshitaka Fujii, Hirotaka Iwase

  Source: Endocrine-related cancer. 2008 Sep

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• Involvement of histone H1.2 in apoptosis induced by DNA double-strand breaks.

  It is poorly understood how apoptotic signals arising from DNA damage are transmitted to mitochondria, which release apoptogenic factors into the cyto…

  Authors: Akimitsu Konishi, Shigeomi Shimizu, Junko Hirota, Toshifumi Takao, Yuhong Fan, Yosuke Matsuoka, Lilin Zhang, Yoshihiro Yoneda, Yoshitaka Fujii, Arthur I Skoultchi,…

  Source: Cell. 2003 Sep 19

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• The utility of antiemetics in the prevention and treatment of postoperative nausea and vomiting in patients scheduled for laparoscopic cholecystectomy.

  Postoperative nausea and vomiting (PONV) are distressing and frequent adverse events of anesthesia and surgery, with a relatively high incidence after…

  Authors: Yoshitaka Fujii

  Source: Current pharmaceutical design. 2005

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• A comparison of pretreatment with fentanyl and lidocaine preceded by venous occlusion for reducing pain on injection of propofol: a prospective, randomized, double-blind, placebo-controlled study in adult Japanese surgical patients.

  BACKGROUND: Pain on injection is a recognized adverse effect of propofol, an agent used to induce general anesthesia in surgical patients. Pretreatmen…

  Authors: Yoshitaka Fujii, Michiyo Itakura

  Source: Clinical therapeutics. 2009 Oct

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• Pretreatment with flurbiprofen axetil, flurbiprofen axetil preceded by venous occlusion, and a mixture of flurbiprofen axetil and propofol in reducing pain on injection of propofol in adult Japanese surgical patients: a prospective, randomized, double-blind, placebo-controlled study.

  BACKGROUND: Pain on injection of propofol is a common clinical problem. Flurbiprofen axetil, an injectable prodrug of flurbiprofen, with or without ve…

  Authors: Yoshitaka Fujii, Michiyo Itakura

  Source: Clinical therapeutics. 2009 Apr

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• Characterizing the cancer genome in lung adenocarcinoma.

  Somatic alterations in cellular DNA underlie almost all human cancers. The prospect of targeted therapies and the development of high-resolution, geno…

  Authors: Barbara A Weir, Michele S Woo, Gad Getz, Sven Perner, Li Ding, Rameen Beroukhim, William M Lin, Michael A Province, Aldi Kraja, Laura A Johnson,…

  Source: Nature. 2007 Dec 6

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• Comparison of propofol, droperidol, and metoclopramide for prophylaxis of postoperative nausea and vomiting after breast cancer surgery: a prospective, randomized, double-blind, placebo-controlled study in Japanese patients.

  BACKGROUND: Breast cancer surgery performed with the patient under general anesthesia has been associated with a relatively high incidence of postoper…

  Authors: Yoshitaka Fujii, Michiyo Itakura

  Source: Clinical therapeutics. 2008 Nov

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• Comparison of lidocaine, metoclopramide, and flurbiprofen axetil for reducing pain on injection of propofol in Japanese adult surgical patients: a prospective, randomized, double-blind, parallel-group, placebo-controlled study.

  BACKGROUND: Pain on injection is a recognized adverse event (AE) of propofol administration for the induction of general anesthesia. Pretreatment with…

  Authors: Yoshitaka Fujii, Michiyo Itakura

  Source: Clinical therapeutics. 2008 Feb

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• Prevention of pain due to injection of propofol with IV administration of lidocaine 40 mg + metoclopramide 2.5, 5, or 10 mg or saline: a randomized, double-blind study in Japanese adult surgical patients.

  BACKGROUND: Pain on injection is a recognized adverse event (AE) with propofol, an agent used to induce general anesthesia in surgical patients. Lidoc…

  Authors: Yoshitaka Fujii, Masahiro Nakayama

  Source: Clinical therapeutics. 2007 May

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