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Influenza viruses cause annual epidemics and occasional pandemics that have claimed the lives of millions. The emergence of new strains will continue …
Authors: Gabriele Neumann, Takeshi Noda, Yoshihiro Kawaoka
Source: Nature. 2009 Jun 18
View Full TextAll viruses rely on host cell proteins and their associated mechanisms to complete the viral life cycle. Identifying the host molecules that participa…
Authors: Linhui Hao, Akira Sakurai, Tokiko Watanabe, Ericka Sorensen, Chairul A Nidom, Michael A Newton, Paul Ahlquist, Yoshihiro Kawaoka
Source: Nature. 2008 Aug 14
View Free Full TextAlthough more than 100 people have been infected by H5N1 influenza A viruses, human-to-human transmission is rare. What are the molecular barriers lim…
Authors: Kyoko Shinya, Masahito Ebina, Shinya Yamada, Masao Ono, Noriyuki Kasai, Yoshihiro Kawaoka
Source: Nature. 2006 Mar 23
View Full TextIn viruses, as in eukaryotes, elaborate mechanisms have evolved to protect the genome and to ensure its timely replication and reliable transmission t…
Authors: Takeshi Noda, Hiroshi Sagara, Albert Yen, Ayato Takada, Hiroshi Kida, R Holland Cheng, Yoshihiro Kawaoka
Source: Nature. 2006 Jan 26
View Full TextHighly pathogenic H5N1 influenza A viruses have spread relentlessly across the globe since 2003, and they are associated with widespread death in poul…
Authors: Andrea Gambotto, Simon M Barratt-Boyes, Menno D de Jong, Gabriele Neumann, Yoshihiro Kawaoka
Source: Lancet. 2008 Apr 26
View Full TextThe 1918 influenza pandemic was unusually severe, resulting in about 50 million deaths worldwide. The 1918 virus is also highly pathogenic in mice, an…
Authors: Darwyn Kobasa, Steven M Jones, Kyoko Shinya, John C Kash, John Copps, Hideki Ebihara, Yasuko Hatta, Jin Hyun Kim, Peter Halfmann, Masato Hatta,…
Source: Nature. 2007 Jan 18
View Full TextRecent outbreaks of highly pathogenic avian influenza A virus (H5N1 subtype) infections in poultry and humans (through direct contact with infected bi…
Authors: Taisuke Horimoto, Yoshihiro Kawaoka
Source: Trends in molecular medicine. 2006 Nov
View Full TextTransfer of viruses between hosts to create a new self-sustaining epidemic is rare; however, those new viruses can cause severe outbreaks. Examples of…
Authors: Colin R Parrish, Yoshihiro Kawaoka
Source: Annual review of microbiology. 2005
View Full TextThe Ebolavirus matrix protein VP40 is essential for virion assembly and egress. Recently, we reported that the COPII transport system plays an importa…
Authors: Seiya Yamayoshi, Gabriele Neumann, Yoshihiro Kawaoka
Source: Journal of virology. 2010 Feb 17
View Full TextInfluenza A viruses cause recurrent outbreaks at local or global scale with potentially severe consequences for human health and the global economy. R…
Authors: Yasushi Itoh, Kyoko Shinya, Maki Kiso, Tokiko Watanabe, Yoshihiro Sakoda, Masato Hatta, Yukiko Muramoto, Daisuke Tamura, Yuko Sakai-Tagawa, Takeshi Noda,…
Source: Nature. 2009 Aug 20
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