1 to 10 of 89 literature results

• Common variants in the GDF5-UQCC region are associated with variation in human height.

  Identifying genetic variants that influence human height will advance our understanding of skeletal growth and development. Several rare genetic varia…

  Authors: Serena Sanna, Anne U Jackson, Ramaiah Nagaraja, Cristen J Willer, Wei-Min Chen, Lori L Bonnycastle, Haiqing Shen, Nicholas Timpson, Guillaume Lettre, Gianluca Usala,…

  Source: Nature genetics. 2008 Feb

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• Modeling the need for hip and knee replacement surgery. Part 2. Incorporating census data to provide small-area predictions for need with uncertainty bounds.

  OBJECTIVE: To develop methods to produce small-area estimates of need for hip and knee replacement surgery to inform local health service planning. ME…

  Authors: Andy Judge, Nicky J Welton, Jat Sandhu, Yoav Ben-Shlomo

  Source: Arthritis and rheumatism. 2009 Dec 15

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• Modeling the need for hip and knee replacement surgery. Part 1. A two-stage cross-cohort approach.

  OBJECTIVE: To explore inequalities in the need for hip/knee replacement surgery using a 2-stage cross-cohort approach. METHODS: In the first stage, a …

  Authors: Andy Judge, Nicky J Welton, Jat Sandhu, Yoav Ben-Shlomo

  Source: Arthritis and rheumatism. 2009 Dec 15

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• Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

  To identify genetic variants influencing plasma lipid concentrations, we first used genotype imputation and meta-analysis to combine three genome-wide…

  Authors: Cristen J Willer, Serena Sanna, Anne U Jackson, Angelo Scuteri, Lori L Bonnycastle, Robert Clarke, Simon C Heath, Nicholas J Timpson, Samer S Najjar, Heather M Stringham,…

  Source: Nature genetics. 2008 Feb

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• Which hemostatic markers add to the predictive value of conventional risk factors for coronary heart disease and ischemic stroke? The Caerphilly Study.

  BACKGROUND: Few studies have examined whether hemostatic markers contribute to risk of coronary disease and ischemic stroke independently of conventio…

  Authors: Ann Smith, Chris Patterson, John Yarnell, Ann Rumley, Yoav Ben-Shlomo, Gordon Lowe

  Source: Circulation. 2005 Nov 15

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• Low birth weight is associated with higher adult total cholesterol concentration in men: findings from an occupational cohort of 25,843 employees.

  BACKGROUND: The majority of studies investigating the association between birth weight and adult total cholesterol (TC) concentration have been small …

  Authors: Anna A Davies, George Davey Smith, Yoav Ben-Shlomo, Paul Litchfield

  Source: Circulation. 2004 Sep 7

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• Cortisol, testosterone, and coronary heart disease: prospective evidence from the Caerphilly study.

  BACKGROUND: There is a popular belief that chronic stress causes heart disease through psychoneuroendocrine mechanisms. We have examined whether an el…

  Authors: George Davey Smith, Yoav Ben-Shlomo, Andrew Beswick, John Yarnell, Stafford Lightman, Peter Elwood

  Source: Circulation. 2005 Jul 19

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• Type 2 diabetes TCF7L2 risk genotypes alter birth weight: a study of 24,053 individuals.

  The role of genes in normal birth-weight variation is poorly understood, and it has been suggested that the genetic component of fetal growth is small…

  Authors: Rachel M Freathy, Michael N Weedon, Amanda Bennett, Elina Hypponen, Caroline L Relton, Beatrice Knight, Beverley Shields, Kirstie S Parnell, Christopher J Groves, Susan M Ring,…

  Source: American journal of human genetics. 2007 Jun

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• Association between C-reactive protein genotype, circulating levels, and aortic pulse wave velocity.

  Circulating C-reactive protein (CRP) level is associated with cardiovascular disease. Whether this relationship is causal has been subject of debate, …

  Authors: Wiebke Schumacher, John Cockcroft, Nicholas J Timpson, Carmel M McEniery, John Gallacher, Ann Rumley, Gordon Lowe, George Davey Smith, Ian B Wilkinson, Yoav Ben-Shlomo

  Source: Hypertension. 2009 Feb

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• Immediate postnatal growth is associated with blood pressure in young adulthood: the Barry Caerphilly Growth Study.

  There is a consistent inverse association between birth weight and systolic blood pressure; however, few studies have been able to examine the immedia…

  Authors: Yoav Ben-Shlomo, Anne McCarthy, Rachael Hughes, Kate Tilling, David Davies, George Davey Smith

  Source: Hypertension. 2008 Oct

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