1 to 10 of 23 literature results

• Microarray-based genomic DNA profiling technologies in clinical molecular diagnostics.

  BACKGROUND: Microarray-based genomic DNA profiling (MGDP) technologies are rapidly moving from translational research to clinical diagnostics and have…

  Authors: Yiping Shen, Bai-Lin Wu

  Source: Clinical chemistry. 2009 Apr

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• Downregulated microRNA-200a in meningiomas promotes tumor growth by reducing E-cadherin and activating the Wnt/beta-catenin signaling pathway.

  Meningiomas, one of the most common human brain tumors, are derived from arachnoidal cells associated with brain meninges, are usually benign, and are…

  Authors: Okay Saydam, Yiping Shen, Thomas Würdinger, Ozlem Senol, Elvan Boke, Marianne F James, Bakhos A Tannous, Anat O Stemmer-Rachamimov, Ming Yi, Robert M Stephens,…

  Source: Molecular and cellular biology. 2009 Nov

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• Genomic dissection of population substructure of Han Chinese and its implication in association studies.

  To date, most genome-wide association studies (GWAS) and studies of fine-scale population structure have been conducted primarily on Europeans. Han Ch…

  Authors: Shuhua Xu, Xianyong Yin, Shilin Li, Wenfei Jin, Haiyi Lou, Ling Yang, Xiaohong Gong, Hongyan Wang, Yiping Shen, Xuedong Pan,…

  Source: American journal of human genetics. 2009 Dec

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• Angiogenin loss-of-function mutations in amyotrophic lateral sclerosis.

  OBJECTIVE: Heterozygous missense mutations in the coding region of angiogenin (ANG), an angiogenic ribonuclease, have been reported in amyotrophic lat…

  Authors: David Wu, Wenhao Yu, Hiroko Kishikawa, Rebecca D Folkerth, A John Iafrate, Yiping Shen, Winnie Xin, Katherine Sims, Guo-Fu Hu

  Source: Annals of neurology. 2007 Dec

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• Disruption of neurexin 1 associated with autism spectrum disorder.

  Autism is a neurodevelopmental disorder of complex etiology in which genetic factors play a major role. We have implicated the neurexin 1 (NRXN1) gene…

  Authors: Hyung-Goo Kim, Shotaro Kishikawa, Anne W Higgins, Ihn-Sik Seong, Diana J Donovan, Yiping Shen, Eric Lally, Lauren A Weiss, Juliane Najm, Kerstin Kutsche,…

  Source: American journal of human genetics. 2008 Jan

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• Characterization of apparently balanced chromosomal rearrangements from the developmental genome anatomy project.

  Apparently balanced chromosomal rearrangements in individuals with major congenital anomalies represent natural experiments of gene disruption and dys…

  Authors: Anne W Higgins, Fowzan S Alkuraya, Amy F Bosco, Kerry K Brown, Gail A P Bruns, Diana J Donovan, Robert Eisenman, Yanli Fan, Chantal G Farra, Heather L Ferguson,…

  Source: American journal of human genetics. 2008 Mar

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• Development of a focused oligonucleotide-array comparative genomic hybridization chip for clinical diagnosis of genomic imbalance.

  BACKGROUND: Submicroscopic genomic imbalance underlies well-defined microdeletion and microduplication syndromes and contributes to general developmen…

  Authors: Yiping Shen, Mira Irons, David T Miller, Sau Wai Cheung, Va Lip, Xiaoming Sheng, Keith Tomaszewicz, Hong Shao, Hong Fang, Hung Siv Tang,…

  Source: Clinical chemistry. 2007 Dec

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• Large-scale medical resequencing for X-linked mental retardation.

  Authors: Yiping Shen, Bai-Lin Wu, James F Gusella

  Source: Clinical chemistry. 2010 Mar

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• Distinct and novel SLC26A4/Pendrin mutations in Chinese and U.S. patients with nonsyndromic hearing loss.

  Mutations of the human SLC26A4/PDS gene constitute the most common cause of syndromic and nonsyndromic hearing loss. Definition of the SLC26A4 mutatio…

  Authors: Pu Dai, Andrew K Stewart, Fouad Chebib, Ann Hsu, Julia Rozenfeld, Deliang Huang, Dongyang Kang, Va Lip, Hong Fang, Hong Shao,…

  Source: Physiological genomics. 2009 Aug 7

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• Genetic testing for developmental delay: keep searching for an answer.

  Authors: David T Miller, Yiping Shen, David J Harris, Bai-Lin Wu, Magdi M Sobeih

  Source: Clinical chemistry. 2009 Apr

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