1 to 10 of 366 literature results

• Molecular identification of the CRAC channel by altered ion selectivity in a mutant of Orai.

  Recent RNA interference screens have identified several proteins that are essential for store-operated Ca2+ influx and Ca2+ release-activated Ca2+ (CR…

  Authors: Andriy V Yeromin, Shenyuan L Zhang, Weihua Jiang, Ying Yu, Olga Safrina, Michael D Cahalan

  Source: Nature. 2006 Sep 14

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• Genetic model of selective COX2 inhibition reveals novel heterodimer signaling.

  Selective inhibitors of cyclooxygenase-2 (COX2) have attracted widespread media attention because of evidence of an elevated risk of cardiovascular co…

  Authors: Ying Yu, Jinjin Fan, Xin-Sheng Chen, Dairong Wang, Andres J Klein-Szanto, Robert L Campbell, Garret A FitzGerald, Colin D Funk

  Source: Nature medicine. 2006 Jun

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• STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane.

  As the sole Ca2+ entry mechanism in a variety of non-excitable cells, store-operated calcium (SOC) influx is important in Ca2+ signalling and many oth…

  Authors: Shenyuan L Zhang, Ying Yu, Jack Roos, J Ashot Kozak, Thomas J Deerinck, Mark H Ellisman, Kenneth A Stauderman, Michael D Cahalan

  Source: Nature. 2005 Oct 6

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• Human C-Reactive Protein Does Not Promote Atherosclerosis in Transgenic Rabbits.

  BACKGROUND: -Although there is a statistically significant association between modestly raised baseline plasma C-reactive protein (CRP) values and fut…

  Authors: Tomonari Koike, Shuji Kitajima, Ying Yu, Kazutoshi Nishijima, Jifeng Zhang, Yukio Ozaki, Masatoshi Morimoto, Teruo Watanabe, Sucharit Bhakdi, Yujiro Asada,…

  Source: Circulation. 2009 Nov 9

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• BCR-ABL1 alters SDF-1alpha-mediated adhesive responses through the beta2 integrin LFA-1 in leukemia cells.

  Stromal-derived factor-1 (SDF-1) and its receptor, CXCR4, are essential for normal hematopoietic progenitor cell movement and adherence within the bon…

  Authors: Ying-Yu Chen, Mobeen Malik, Brian E Tomkowicz, Ronald G Collman, Andrzej Ptasznik

  Source: Blood. 2008 May 15

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• High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity.

  BACKGROUND & AIMS: The composition of the gut microbiome is affected by host phenotype, genotype, immune function, and diet. Here, we used the phenoty…

  Authors: Marie A Hildebrandt, Christian Hoffman, Scott A Sherrill-Mix, Sue A Keilbaugh, Micah Hamady, Ying-Yu Chen, Rob Knight, Rexford S Ahima, Frederic Bushman, Gary D Wu

  Source: Gastroenterology. 2009 Aug 23

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• A functional single-nucleotide polymorphism in the TRPC6 gene promoter associated with idiopathic pulmonary arterial hypertension.

  BACKGROUND: Excessive proliferation of pulmonary artery smooth muscle cells (PASMCs) plays an important role in the development of idiopathic pulmonar…

  Authors: Ying Yu, Steve H Keller, Carmelle V Remillard, Olga Safrina, Ann Nicholson, Shenyuan L Zhang, Weihua Jiang, Nivruthi Vangala, Judd W Landsberg, Jian-Ying Wang,…

  Source: Circulation. 2009 May 5

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• N-amidation by copper-mediated cross-coupling of organostannanes or boronic acids with o-acetyl hydroxamic acids.

  A general nonoxidative N-amidation of organostannanes and boronic acids has been developed. Under nonbasic conditions a wide variety of aryl, alkenyl,…

  Authors: Zhihui Zhang, Ying Yu, Lanny S Liebeskind

  Source: Organic letters. 2008 Jul 17

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• Improved triglyceride transesterification by circular permuted Candida antarctica lipase B.

  Lipases represent a versatile class of biocatalysts with numerous potential applications in industry including the production of biodiesel via enzyme-…

  Authors: Ying Yu, Stefan Lutz

  Source: Biotechnology and bioengineering. 2009 Jul 16

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• X-ray photoelectron spectrometry depth profiling of organic thin films using C60 sputtering.

  A buckminsterfullerene (C(60)) ion beam was used for X-ray photoelectron spectrometry depth profiling of various organic thin films. Specimens represe…

  Authors: Ying-Yu Chen, Bang-Ying Yu, Wei-Ben Wang, Mao-Feng Hsu, Wei-Chun Lin, Yu-Chin Lin, Jwo-Huei Jou, Jing-Jong Shyue

  Source: Analytical chemistry. 2008 Jan 15

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