1 to 10 of 395 literature results

• Forgetting is regulated through Rac activity in Drosophila.

  Initially acquired memory dissipates rapidly if not consolidated. Such memory decay is thought to result either from the inherently labile nature of n…

  Authors: Yichun Shuai, Binyan Lu, Ying Hu, Lianzhang Wang, Kan Sun, Yi Zhong

  Source: Cell. 2010 Feb 19

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• The XIST noncoding RNA functions independently of BRCA1 in X inactivation.

  Females with germline mutations in BRCA1 are predisposed to develop breast and ovarian cancers. A previous report indicated that BRCA1 colocalizes wit…

  Authors: Cuiying Xiao, Judith A Sharp, Misako Kawahara, Albert R Davalos, Michael J Difilippantonio, Ying Hu, Wenmei Li, Liu Cao, Ken Buetow, Thomas Ried,…

  Source: Cell. 2007 Mar 9

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• Surface-structure-regulated cell-membrane penetration by monolayer-protected nanoparticles.

  Nanoscale objects are typically internalized by cells into membrane-bounded endosomes and fail to access the cytosolic cell machinery. Whereas some bi…

  Authors: Ayush Verma, Oktay Uzun, Yuhua Hu, Ying Hu, Hee-Sun Han, Nicki Watson, Suelin Chen, Darrell J Irvine, Francesco Stellacci

  Source: Nature materials. 2008 Jul

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• Suppression of colorectal oncogenesis by selenium-enriched milk proteins: apoptosis and K-ras mutations.

  The chemical form and bioavailability of dietary selenium may influence its protectiveness against colorectal cancer. Selenium is readily incorporated…

  Authors: Ying Hu, Graeme H McIntosh, Richard K Le Leu, Richard Woodman, Graeme P Young

  Source: Cancer research. 2008 Jun 15

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• Neurotrophic effect of a novel TrkB agonist on retinal ganglion cells.

  PURPOSE: Retinal ganglion cells (RGCs) die in glaucoma and virtually all optic neuropathies. Recently, novel tropomyosin-related kinase B (TrkB) monoc…

  Authors: Ying Hu, Seongeun Cho, Jeffrey L Goldberg

  Source: Investigative ophthalmology & visual science. 2010 Mar

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• Identification of a novel mouse P4-ATPase family member highly expressed during spermatogenesis.

  P4-ATPases are transmembrane proteins unique to eukaryotes that play a fundamental role in vesicular transport. They have been proposed to act as phos…

  Authors: Peng Xu, Juha Okkeri, Susanne Hanisch, Rui-Ying Hu, Qin Xu, Thomas Günther Pomorski, Xiao-Yan Ding

  Source: Journal of cell science. 2009 Aug 15

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• Insulin receptor substrate-1 suppresses transforming growth factor-beta1-mediated epithelial-mesenchymal transition.

  We investigated the regulatory effect of insulin receptor substrate-1 (IRS-1) on transforming growth factor-beta1 (TGF-beta1)-induced epithelial-mesen…

  Authors: Jian Shi, Dong-Mei Wang, Chun-Mei Wang, Ying Hu, Ai-Hua Liu, Yong-Lian Zhang, Bing Sun, Jian-Guo Song

  Source: Cancer research. 2009 Sep 15

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• Ferritin heavy chain-mediated iron homeostasis and subsequent increased reactive oxygen species production are essential for epithelial-mesenchymal transition.

  The epithelial-mesenchymal transition (EMT) plays a critical role in tumor progression. To obtain a broad view of the molecules involved in EMT, we ca…

  Authors: Ke-Hua Zhang, Hong-Yu Tian, Xia Gao, Wei-Wei Lei, Ying Hu, Dong-Mei Wang, Xin-Chao Pan, Mei-Lan Yu, Gen-Jun Xu, Fu-Kun Zhao,…

  Source: Cancer research. 2009 Jul 1

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• Deletion of the inducible 70-kDa heat shock protein genes in mice impairs cardiac contractile function and calcium handling associated with hypertrophy.

  BACKGROUND: Hspa1a and Hspa1b genes encode stress-inducible 70-kDa heat shock proteins (Hsp70) that protect cells from insults such as ischemia. Mice …

  Authors: Yun-Kyung Kim, Jorge Suarez, Ying Hu, Patrick M McDonough, Christa Boer, David J Dix, Wolfgang H Dillmann

  Source: Circulation. 2006 Jun 6

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• Evidence of epistasis between the catechol-O-methyltransferase and aldehyde dehydrogenase 3B1 genes in paranoid schizophrenia.

  BACKGROUND: Schizophrenia is a common yet severe psychiatric condition characterized by complex genetic mechanism and diverse clinical presentations. …

  Authors: Yan Wang, Ying Hu, Yue Fang, Kerang Zhang, Hong Yang, Jintang Ma, Qi Xu, Yan Shen

  Source: Biological psychiatry. 2009 Jun 15

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