1 to 10 of 49 literature results

• Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.

  Aggrecan cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 5 (ADAMTS-5) is crucial for the breakdown of carti…

  Authors: Frank Echtermeyer, Jessica Bertrand, Rita Dreier, Ingmar Meinecke, Katja Neugebauer, Martin Fuerst, Yun Jong Lee, Yeong Wook Song, Christine Herzog, Gregor Theilmeier,…

  Source: Nature medicine. 2009 Sep

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• Evidence of potential interaction of chemokine genes in susceptibility to systemic sclerosis.

  OBJECTIVE: To examine genetic polymorphisms in the chemokine pathway, and to assess their interactions in relation to susceptibility to systemic scler…

  Authors: Eun Bong Lee, Jinying Zhao, Jeong Yeon Kim, Momiao Xiong, Yeong Wook Song

  Source: Arthritis and rheumatism. 2007 Jul

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• Downregulation of heat shock protein 70 protects rheumatoid arthritis fibroblast-like synoviocytes from nitric oxide-induced apoptosis.

  INTRODUCTION: Heat shock protein 70 (Hsp70) is a well-known anti-apoptotic protein that blocks multiple steps in the stress-induced apoptotic pathway.…

  Authors: Eun Ha Kang, Dong Jo Kim, Eun Young Lee, Yun Jong Lee, Eun Bong Lee, Yeong Wook Song

  Source: Arthritis research & therapy. 2009

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• HLA-DPB1 and DPB2 are genetic loci for systemic sclerosis: a genome-wide association study in Koreans with replication in North Americans.

  OBJECTIVE: To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study. METHODS: A genome-wide association study was …

  Authors: Xiaodong Zhou, Jong Eun Lee, Frank C Arnett, Momiao Xiong, Min Young Park, Yeon Kyeong Yoo, Eun Soon Shin, John D Reveille, Maureen D Mayes, Jin Hyun Kim,…

  Source: Arthritis and rheumatism. 2009 Dec

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• Reciprocal cross-talk between RANKL and interferon-gamma-inducible protein 10 is responsible for bone-erosive experimental arthritis.

  OBJECTIVE: Interferon-gamma-inducible protein 10 (IP-10; also called CXCL10), a chemokine important in the migration and proliferation of T cells, is …

  Authors: Han Bok Kwak, Hyunil Ha, Ha-Neui Kim, Jong-Ho Lee, Hun Soo Kim, Seungbok Lee, Hyun-Man Kim, Jung Yeon Kim, Hong-Hee Kim, Yeong Wook Song,…

  Source: Arthritis and rheumatism. 2008 May

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• Associations between interferon regulatory factor-1 polymorphisms and Behçet's disease.

  Interferon regulatory factor-1 (IRF-1) is a transcription factor that regulates the functions of type I and II interferons and plays a role in host pr…

  Authors: Yun Jong Lee, Seong Wook Kang, Ju Kyoung Song, Han Joo Baek, Hyo Jin Choi, Young Deok Bae, Hee Jung Ryu, Eun Young Lee, Eun Bong Lee, Yeong Wook Song

  Source: Human immunology. 2007 Sep

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• HLA-DQA1 is not an apparent risk factor for microchimerism in patients with various autoimmune diseases and in healthy individuals.

  OBJECTIVE: Microchimeric cells have been identified in lesions and peripheral blood of patients with systemic sclerosis (SSc) and idiopathic inflammat…

  Authors: Carol M Artlett, Terrence P O'Hanlon, Ana M Lopez, Yeong Wook Song, Frederick W Miller, Lisa G Rider

  Source: Arthritis and rheumatism. 2003 Sep

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• Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients.

  BACKGROUND:S-adenosylmethionine (SAMe) has antiinflammatory and analgesie effects and has been reported to ameliorate the pain and dysfunction of oste…

  Authors: Jinhyun Kim, Eun Young Lee, Eun-Mi Koh, Hoon-Suk Cha, Bin Yoo, Chang Keun Lee, Yun Jong Lee, Heejung Ryu, Ki Hoon Lee, Yeong Wook Song

  Source: Clinical therapeutics. 2009 Dec

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• Association between the MLH1 gene and longevity.

  Perturbations in genomic stability result in cancer, a reduced life span, and premature aging. MLH1 is a mismatch repair enzyme that acts to maintain …

  Authors: Dong Jo Kim, Sang Mi Yi, Seung Yeon Lee, Heun Soo Kang, Yoon-Ho Choi, Yeong Wook Song, Sang Chul Park

  Source: Human genetics. 2006 Apr

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• Matrix metalloproteinase-9 promoter polymorphisms in Korean patients with systemic lupus erythematosus.

  To investigate the association between functional promoter polymorphisms of matrix metalloproteinase-9 (MMP-9) and systemic lupus erythematosus (SLE),…

  Authors: Yun Jong Lee, Mijung Woo, Jung-Hyun Nam, Jinah Baek, Churl Hyun Im, Eun Young Lee, Eun Bong Lee, Kyung Sook Park, Yeong Wook Song

  Source: Human immunology. 2008 Jun

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