1 to 10 of 5,386 literature results

• Neurophysiology: Hodgkin and Huxley model--still standing?

  Action potentials in cortical neurons show a variable threshold and a sudden rise in membrane potential at initiation. Naundorf et al. fail to explain…

  Authors: David A McCormick, Yousheng Shu, Yuguo Yu

  Source: Nature. 2007 Jan 4

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• FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter.

  Transcriptional activators and coactivators overcome repression by chromatin, but regulation of chromatin disassembly and coactivator binding to promo…

  Authors: Shinya Takahata, Yaxin Yu, David J Stillman

  Source: Molecular cell. 2009 May 14

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• Iodine/iodide-free dye-sensitized solar cells.

  Dye-sensitized solar cells (DSSCs) are built from nanocrystalline anatase TiO(2) with a 101 crystal face (nc-TiO(2)) onto which a dye is absorbed, rut…

  Authors: Shozo Yanagida, Youhai Yu, Kazuhiro Manseki

  Source: Accounts of chemical research. 2009 Nov 17

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• Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity.

  Humans are colonized by a large and diverse bacterial flora (the microbiota) essential for the development of the gut immune system. A broader role fo…

  Authors: Thomas B Clarke, Kimberly M Davis, Elena S Lysenko, Alice Y Zhou, Yimin Yu, Jeffrey N Weiser

  Source: Nature medicine. 2010 Feb

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• Phosphatase SHP-1 promotes TLR- and RIG-I-activated production of type I interferon by inhibiting the kinase IRAK1.

  Unbalanced production of proinflammatory cytokines and type I interferons in immune responses may lead to immunopathology; thus, the mechanisms that e…

  Authors: Huazhang An, Jin Hou, Jun Zhou, Wei Zhao, Hongmei Xu, Yuejuan Zheng, Yizhi Yu, Shuxun Liu, Xuetao Cao

  Source: Nature immunology. 2008 May

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• LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.

  Lysine-specific demethylase 1 (LSD1) exerts pathway-specific activity in animal development and has been linked to several high-risk cancers. Here, we…

  Authors: Yan Wang, Hua Zhang, Yupeng Chen, Yimin Sun, Fen Yang, Wenhua Yu, Jing Liang, Luyang Sun, Xiaohan Yang, Lei Shi,…

  Source: Cell. 2009 Aug 21

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• Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential.

  Traditionally, neuronal operations in the cerebral cortex have been viewed as occurring through the interaction of synaptic potentials in the dendrite…

  Authors: Yousheng Shu, Andrea Hasenstaub, Alvaro Duque, Yuguo Yu, David A McCormick

  Source: Nature. 2006 Jun 8

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• Emotion recollected in tranquility: lessons learned from the COX-2 saga.

  Nonsteroidal antinflammatory drugs (NSAIDs) inhibit prostaglandin formation by cyclooxygenases (COX) 1 and 2. NSAIDs selective for inhibition of COX-2…

  Authors: Tilo Grosser, Ying Yu, Garret A Fitzgerald

  Source: Annual review of medicine. 2010

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• Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp.

  Bacteria employ a coordinated SOS response to DNA damage by enhancing transcription, translesion synthesis, and recombination; a similar phenomenon ha…

  Authors: Yu Fu, Yu Zhu, Ke Zhang, Mantek Yeung, Daniel Durocher, Wei Xiao

  Source: Cell. 2008 May 16

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• Dendritic signalling and homeostatic adaptation.

  Homeostatic plasticity mechanisms are employed by neurons to alter membrane excitability and synaptic strength to adapt to changes in network activity…

  Authors: Lily M Y Yu, Yukiko Goda

  Source: Current opinion in neurobiology. 2009 Jun

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