1 to 10 of 705 literature results

• Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.

  Ultraviolet (UV) light-induced pyrimidine photodimers are repaired by the nucleotide excision repair pathway. Photolesions have biophysical parameters…

  Authors: Andrea Scrima, Renata Konícková, Bryan K Czyzewski, Yusuke Kawasaki, Philip D Jeffrey, Regina Groisman, Yoshihiro Nakatani, Shigenori Iwai, Nikola P Pavletich, Nicolas H Thomä

  Source: Cell. 2008 Dec 26

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• Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic pain.

  Treatment of neuropathic pain, triggered by multiple insults to the nervous system, is a clinical challenge because the underlying mechanisms of neuro…

  Authors: Yasuhiko Kawasaki, Zhen-Zhong Xu, Xiaoying Wang, Jong Yeon Park, Zhi-Ye Zhuang, Ping-Heng Tan, Yong-Jing Gao, Kristine Roy, Gabriel Corfas, Eng H Lo,…

  Source: Nature medicine. 2008 Mar

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• Carminerin contributes to chondrocyte calcification during endochondral ossification.

  Endochondral ossification is an essential process not only for physiological skeletal development and growth, but also for pathological disorders. We …

  Authors: Takashi Yamada, Hirotaka Kawano, Yu Koshizuka, Toru Fukuda, Kimihiro Yoshimura, Satoru Kamekura, Taku Saito, Toshiyuki Ikeda, Yosuke Kawasaki, Yoshiaki Azuma,…

  Source: Nature medicine. 2006 Jun

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• Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination.

  Meiosis ensures genetic diversification of gametes and sexual reproduction. For successful meiosis, multiple events such as DNA replication, recombina…

  Authors: Hiroyuki Sasanuma, Kouji Hirota, Tomoyuki Fukuda, Naoko Kakusho, Kazuto Kugou, Yasuo Kawasaki, Takehiko Shibata, Hisao Masai, Kunihiro Ohta

  Source: Genes & development. 2008 Feb 1

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• Mutated APC and Asef are involved in the migration of colorectal tumour cells.

  The tumour suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumours. APC binds to beta-catenin, a key compon…

  Authors: Yoshihiro Kawasaki, Rina Sato, Tetsu Akiyama

  Source: Nature cell biology. 2003 Mar

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• Progressive gray matter reduction of the superior temporal gyrus during transition to psychosis.

  CONTEXT: Longitudinal magnetic resonance imaging studies have shown progressive gray matter reduction in the superior temporal gyrus during the earlie…

  Authors: Tsutomu Takahashi, Stephen J Wood, Alison R Yung, Bridget Soulsby, Patrick D McGorry, Michio Suzuki, Yasuhiro Kawasaki, Lisa J Phillips, Dennis Velakoulis, Christos Pantelis

  Source: Archives of general psychiatry. 2009 Apr

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• Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.

  The tumor suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumors. APC interacts with the Rac1- and Cdc42-sp…

  Authors: M Sagara, Y Kawasaki, S-i Iemura, T Natsume, Y Takai, T Akiyama

  Source: Oncogene. 2009 Mar 12

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• Truncation mutations abolish chromatin-associated activities of adenomatous polyposis coli.

  The adenomatous polyposis coli (APC) is a tumor suppressor whose loss of function leads to colon cancer. APC shuttles between the nucleus and cytoplas…

  Authors: A P Kouzmenko, K Takeyama, Y Kawasaki, T Akiyama, S Kato

  Source: Oncogene. 2008 Aug 21

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• The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.

  Sporadic and familial colorectal tumours usually harbour biallelic adenomatous polyposis coli (APC)-associated mutations that result in constitutive a…

  Authors: Yoshihiro Kawasaki, Shinnosuke Tsuji, Ken Muroya, Shiori Furukawa, Yoko Shibata, Masumi Okuno, Susumu Ohwada, Tetsu Akiyama

  Source: EMBO reports. 2009 Dec

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• Wnt signalling and the actin cytoskeleton.

  The tumour suppressor adenomatous polyposis coli (APC) is mutated in sporadic and familial colorectal tumours. APC binds to beta-catenin, a key compon…

  Authors: T Akiyama, Y Kawasaki

  Source: Oncogene. 2006 Dec 4

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