1 to 10 of 1,023 literature results

• Homeostasis established by coordination of subcellular compartment plasticity improves spike encoding.

  Homeostasis in cells maintains their survival and functions. The plasticity at neurons and synapses may destabilize their signal encoding. The rapid r…

  Authors: Na Chen, Xin Chen, Jin-Hui Wang

  Source: Journal of cell science. 2008 Sep 1

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• Increased expression of integrin-linked kinase attenuates left ventricular remodeling and improves cardiac function after myocardial infarction.

  BACKGROUND: Left ventricular (LV) remodeling is associated with the development of heart failure after myocardial infarction. Here we investigated whe…

  Authors: Liang Ding, Li Dong, Xin Chen, Lujie Zhang, Xiaoyu Xu, Albert Ferro, Biao Xu

  Source: Circulation. 2009 Sep 1

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• Gain and fidelity of transmission patterns at cortical excitatory unitary synapses improve spike encoding.

  Neuronal spike encoding and synaptic transmission in the brain need be precise and reliable for well-organized behavior and cognition. Little is known…

  Authors: Jin-Hui Wang, Jian Wei, Xin Chen, Jiandong Yu, Na Chen, Jack Shi

  Source: Journal of cell science. 2008 Sep 1

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• Decoding global gene expression programs in liver cancer by noninvasive imaging.

  Paralleling the diversity of genetic and protein activities, pathologic human tissues also exhibit diverse radiographic features. Here we show that dy…

  Authors: Eran Segal, Claude B Sirlin, Clara Ooi, Adam S Adler, Jeremy Gollub, Xin Chen, Bryan K Chan, George R Matcuk, Christopher T Barry, Howard Y Chang,…

  Source: Nature biotechnology. 2007 Jun

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• Hydrogen bonding lowers intrinsic nucleophilicity of solvated nucleophiles.

  The relationship between nucleophilicity and the structure/environment of the nucleophile is of fundamental importance in organic chemistry. In this w…

  Authors: Xin Chen, John I Brauman

  Source: Journal of the American Chemical Society. 2008 Nov 12

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• New tools for functional genomic analysis.

  For the past decade, the development of genomic technology has revolutionized modern biological research and drug discovery. Functional genomic analys…

  Authors: Xin Chen, Eric Jorgenson, Siu Tim Cheung

  Source: Drug discovery today. 2009 Aug

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• Frequent inactivation of axon guidance molecule RGMA in human colon cancer through genetic and epigenetic mechanisms.

  BACKGROUND & AIMS: Repulsive guidance molecule member A (RGMA) is a glycosylphosphatidylinositol-anchored glycoprotein and axon guidance molecule that…

  Authors: Vivian S W Li, Siu Tsan Yuen, Tsun Leung Chan, Helen H N Yan, Wai Lun Law, Bonnie H Y Yeung, Annie S Y Chan, Wai Yin Tsui, Samuel So, Xin Chen,…

  Source: Gastroenterology. 2009 Jul

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• PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells.

  Primary keratinocytes exhibit three typical clonal morphologies represented by holoclones, meroclones, and paraclones, with holoclones containing self…

  Authors: Hangwen Li, Xin Chen, Tammy Calhoun-Davis, Kent Claypool, Dean G Tang

  Source: Cancer research. 2008 Mar 15

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• Computational identification of potential molecular interactions in Arabidopsis.

  Knowledge of the protein interaction network is useful to assist molecular mechanism studies. Several major repositories have been established to coll…

  Authors: Mingzhi Lin, Bin Hu, Lijuan Chen, Peng Sun, Yi Fan, Ping Wu, Xin Chen

  Source: Plant physiology. 2009 Sep

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• Templating water stains for nanolithography.

  Herein, a nanoscale patterning technique is demonstrated for creating twin features in polymers and metals. The process works by combining evaporative…

  Authors: Wei-Ssu Liao, Xin Chen, Jixin Chen, Paul S Cremer

  Source: Nano letters. 2007 Aug

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