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10 literature results
Parkinson disease (PD) is a complex, multifactorial neurodegenerative disease with substantial evidence for genetic risk factors. We conducted a genom…
Authors: Xiaoyi Gao, Eden R Martin, Yutao Liu, Gregory Mayhew, Jeffery M Vance, William K Scott
Source: American journal of human genetics. 2009 Apr
View Free Full TextThere is a long history of using allele sharing distance (ASD) and closely related metrics for population stratification analysis. However, the theory…
Authors: Xiaoyi Gao, Eden R Martin
Source: Human heredity. 2009
View Full TextMultiple testing is a challenging issue in genetic association studies using large numbers of single nucleotide polymorphism (SNP) markers, many of wh…
Authors: Xiaoyi Gao, Joshua Starmer, Eden R Martin
Source: Genetic epidemiology. 2008 May
View Full TextA major challenge in genome-wide association studies (GWASs) is to derive the multiple testing threshold when hypothesis tests are conducted using a l…
Authors: Xiaoyi Gao, Lewis C Becker, Diane M Becker, Joshua D Starmer, Michael A Province
Source: Genetic epidemiology. 2010 Jan
View Full TextBACKGROUND: Population structure analysis is important to genetic association studies and evolutionary investigations. Parametric approaches, e.g. STR…
Authors: Xiaoyi Gao, Joshua D Starmer
Source: BMC bioinformatics. 2008
View Full TextBACKGROUND: We describe a hierarchical clustering algorithm for using Single Nucleotide Polymorphism (SNP) genetic data to assign individuals to popul…
Authors: Xiaoyi Gao, Joshua Starmer
Source: BMC genetics. 2007
View Full TextABSTRACT : We investigated the association of metabolic syndrome (MetS) with a 500 k and a 50 k single-nucleotide polymorphism (SNP) gene chip in the …
Authors: Yong-Moon Park, Michael A Province, Xiaoyi Gao, Mary Feitosa, Jun Wu, Duanduan Ma, Dc Rao, Aldi T Kraja
Source: BMC proceedings. 2009
View Full TextThis unit describes the statistical techniques necessary for performing family-based association studies (such as the TDT) for genetic polymorphisms. …
Authors: Warren J Ewens, Richard S Spielman, Norman L Kaplan, Xiaoyi Gao, Richard W Morris, Eden R Martin
Source: Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. 2008 Jul
View Full TextABSTRACT : We examine a Bayesian Markov-chain Monte Carlo framework for simultaneous segregation and linkage analysis in the simulated single-nucleoti…
Authors: E Warwick Daw, Jevon Plunkett, Mary Feitosa, Xiaoyi Gao, Andrew Van Brunt, Duanduan Ma, Jacek Czajkowski, Michael A Province, Ingrid Borecki
Source: BMC proceedings. 2009
View Full TextCentral abdominal fat is a strong risk factor for diabetes and cardiovascular disease. To identify common variants influencing central abdominal fat, …
Authors: Nancy L Heard-Costa, M Carola Zillikens, Keri L Monda, Asa Johansson, Tamara B Harris, Mao Fu, Talin Haritunians, Mary F Feitosa, Thor Aspelund, Gudny Eiriksdottir,…
Source: PLoS genetics. 2009 Jun
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