1 to 7 of 7 literature results

• Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery.

  Previous studies suggest that thymus produces a homogenous population of natural regulatory T (Treg) cells that express a transcriptional factor FOXP3…

  Authors: Tomoki Ito, Shino Hanabuchi, Yi-Hong Wang, Woong Ryeon Park, Kazuhiko Arima, Laura Bover, F Xiao-Feng Qin, Michel Gilliet, Yong-Jun Liu

  Source: Immunity. 2008 Jun

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• p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway.

  Although a number of p53 target genes have been identified, the mechanisms of p53-dependent activities that determine cellular survival or death are s…

  Authors: Woong-Ryeon Park, Yusuke Nakamura

  Source: Cancer research. 2005 Feb 15

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• A mechanism underlying STAT4-mediated up-regulation of IFN-gamma induction inTCR-triggered T cells.

  IL-12 promotes T(h)1 development/IFN-gamma expression by activating STAT4. However, it is still unclear how STAT4 elicits IFN-gamma promoter activatio…

  Authors: Woong-Ryeon Park, Masakiyo Nakahira, Naotoshi Sugimoto, Yang Bian, Yumi Yashiro-Ohtani, Xu-Yu Zhou, Yi-Fu Yang, Toshiyuki Hamaoka, Hiromi Fujiwara

  Source: International immunology. 2004 Feb

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• Reversible CD8 expression induced by common cytokine receptor gamma chain-dependent cytokines in a cloned CD4(+) T(h)1 cell line.

  T cells that are intrathymically lineage committed are believed to maintain their CD4 or CD8 co-receptor expression. Here, we investigated whether int…

  Authors: Cheung-Seog Park, Yi-Fu Yang, Xu-Yu Zhou, Kazuhito Toyooka, Yumi Yashiro-Ohtani, Woong-Ryeon Park, Michio Tomura, Xu-Guang Tai, Toshiyuki Hamaoka, Hiromi Fujiwara

  Source: International immunology. 2002 Mar

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• Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-gamma stimulation.

  The chemokine receptor CXCR3 has been shown to play a key role in the recruitment of T cells to sites of inflammation such as allografts. Here, we inv…

  Authors: Chigusa Nakajima, Takao Mukai, Nobuya Yamaguchi, Yasunari Morimoto, Woong-Ryeon Park, Masayuki Iwasaki, Ping Gao, Shiro Ono, Hiromi Fujiwara, Toshiyuki Hamaoka

  Source: European journal of immunology. 2002 Jun

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• Synergy of IL-12 and IL-18 for IFN-gamma gene expression: IL-12-induced STAT4 contributes to IFN-gamma promoter activation by up-regulating the binding activity of IL-18-induced activator protein 1.

  IL-12 and IL-18 synergistically enhance IFN-gamma mRNA transcription by activating STAT4 and AP-1, respectively. However, it is still unknown how STAT…

  Authors: Masakiyo Nakahira, Hyun-Jong Ahn, Woong-Ryeon Park, Ping Gao, Michio Tomura, Cheung-Seog Park, Toshiyuki Hamaoka, Tsunetaka Ohta, Masashi Kurimoto, Hiromi Fujiwara

  Source: Journal of immunology (Baltimore, Md. : 1950). 2002 Feb 1

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• Molecular mechanisms underlying differential contribution of CD28 versus non-CD28 costimulatory molecules to IL-2 promoter activation.

  T cell costimulation via CD28 and other (non-CD28) costimulatory molecules induces comparable levels of [(3)H]TdR incorporation, but fundamentally dif…

  Authors: Xu-Yu Zhou, Yumi Yashiro-Ohtani, Masakiyo Nakahira, Woong Ryeon Park, Ryo Abe, Toshiyuki Hamaoka, Mayumi Naramura, Hua Gu, Hiromi Fujiwara

  Source: Journal of immunology (Baltimore, Md. : 1950). 2002 Apr 15

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