1 to 10 of 39 literature results

• The MBL2 'LYQA secretor' haplotype is an independent predictor of postoperative myocardial infarction in whites undergoing coronary artery bypass graft surgery.

  BACKGROUND: Mannose-binding lectin (MBL) is an important component of innate immunity and activator of the lectin complement pathway. Within the MBL2 …

  Authors: Charles D Collard, Stanton K Shernan, Amanda A Fox, Toralf Bernig, Stephen J Chanock, William K Vaughn, Kazue Takahashi, Alan B Ezekowitz, Petr Jarolim, Simon C Body

  Source: Circulation. 2007 Sep 11

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• Statins are associated with a reduced incidence of perioperative mortality after coronary artery bypass graft surgery.

  BACKGROUND: Statin therapy in nonsurgical patient populations is associated with a significant reduction in adverse cardiovascular events, including d…

  Authors: Wei Pan, Tatjana Pintar, James Anton, Vei-Vei Lee, William K Vaughn, Charles D Collard

  Source: Circulation. 2004 Sep 14

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• Cyclooxygenase-2 inhibitor treatment improves left ventricular function and mortality in a murine model of doxorubicin-induced heart failure.

  BACKGROUND: Progression of heart failure after initial myocardial injury is mediated in part by various redundant inflammatory mediators, including th…

  Authors: Reynolds M Delgado, Mohamad A Nawar, Aly M Zewail, Biswajit Kar, William K Vaughn, Kenneth K Wu, Nena Aleksic, Natarajan Sivasubramanian, Kathleen McKay, Douglas L Mann,…

  Source: Circulation. 2004 Mar 23

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• Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model.

  BACKGROUND: Bone marrow-derived stem cells are under investigation as a treatment for ischemic heart disease. Mesenchymal stem cells (MSCs) have been …

  Authors: Guilherme V Silva, Silvio Litovsky, Joao A R Assad, Andre L S Sousa, Bradley J Martin, Deborah Vela, Stephanie C Coulter, Jing Lin, Judy Ober, William K Vaughn,…

  Source: Circulation. 2005 Jan 18

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• Obesity in diabetic patients undergoing coronary artery bypass graft surgery is associated with increased postoperative morbidity.

  BACKGROUND: Despite the fact that obesity is a known risk factor for cardiovascular disease, many studies have failed to demonstrate that obesity is i…

  Authors: Wei Pan, Katja Hindler, Vei-Vei Lee, William K Vaughn, Charles D Collard

  Source: Anesthesiology. 2006 Mar

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• Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction.

  This study assessed safety of transendocardial (TE) electromechanical-guided delivery of bone marrow mesenchymal stem cells (MSCs) after acute myocard…

  Authors: Emerson C Perin, Guilherme V Silva, Joao A R Assad, Deborah Vela, L Maximilian Buja, Andre L S Sousa, Silvio Litovsky, Jing Lin, William K Vaughn, Stephanie Coulter,…

  Source: Journal of molecular and cellular cardiology. 2008 Mar

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• Regional myocardial deformation in children with hypertrophic cardiomyopathy: morphological and clinical correlations.

  AIMS: Hypertrophic cardiomyopathy (HCM) is a disease with marked regional differences in wall thickness. However, the relation between myocardial func…

  Authors: Javier Ganame, Luc Mertens, Benjamin W Eidem, Piet Claus, Jan D'hooge, Luke M Havemann, Colin J McMahon, Mac Arthur A Elayda, William K Vaughn, Jeffrey A Towbin,…

  Source: European heart journal. 2007 Dec

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• Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy.

  BACKGROUND: We recently reported the safety and feasibility of autologous bone marrow mononuclear cell (ABMMNC) injection into areas of ischemic myoca…

  Authors: Emerson C Perin, Hans F R Dohmann, Radovan Borojevic, Suzana A Silva, Andre L S Sousa, Guilherme V Silva, Claudio T Mesquita, Luciano Belém, William K Vaughn, Fernando O D Rangel,…

  Source: Circulation. 2004 Sep 14

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• Current expectations for newborns undergoing the arterial switch operation.

  BACKGROUND: The arterial switch operation (ASO) represents a remarkable success story in the surgical treatment of cyanotic congenital heart disease. …

  Authors: Daniel J Dibardino, Andrew E Allison, William K Vaughn, E Dean McKenzie, Charles D Fraser

  Source: Annals of surgery. 2004 May

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• Jugular venous oxygenation during hypothermic cardiopulmonary bypass in patients at risk for abnormal cerebral autoregulation: influence of alpha-Stat versus pH-stat blood gas management.

  In a prospective, randomized study of cardiac surgical patients at risk for impaired cerebral blood flow autoregulation, we compared alpha-stat and pH…

  Authors: Lance R Hoover, Radhika Dinavahi, Wei-Ping Cheng, John R Cooper, Maria Rosa Marino, Tyler C Spata, Gaile L Daniels, William K Vaughn, Nancy A Nussmeier

  Source: Anesthesia and analgesia. 2009 May

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