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1 to 8 of 8 literature results
Industrial penicillin production with the filamentous fungus Penicillium chrysogenum is based on an unprecedented effort in microbial strain improveme…
Authors: Marco A van den Berg, Richard Albang, Kaj Albermann, Jonathan H Badger, Jean-Marc Daran, Arnold J M Driessen, Carlos Garcia-Estrada, Natalie D Fedorova, Diana M Harris, Wilbert H M Heijne,…
Source: Nature biotechnology. 2008 Oct
View Full TextTo contribute to the hazard identification of low molecular weight (LMW) respiratory allergens, respiratory allergy induced by trimellitic anhydride (…
Authors: C Frieke Kuper, Wilbert H M Heijne, Marinus Dansen, Kitty C M Verhoeckx, Andre Boorsma, Marijana Radonjic, Joost Bruijntjes, Rob Stierum, Hans Muijser, Josje H E Arts
Source: Toxicologic pathology. 2008
View Full TextToxicogenomics is a novel approach integrating the expression analysis of thousands of genes (transcriptomics) or proteins (proteomics) with classical…
Authors: Wilbert H M Heijne, Rob H Stierum, Monique Slijper, Peter J van Bladeren, Ben van Ommen
Source: Biochemical pharmacology. 2003 Mar 1
View Full TextThis study investigated whether integrated analysis of transcriptomics and metabolomics data increased the sensitivity of detection and provided new i…
Authors: Wilbert H M Heijne, Robert-Jan A N Lamers, Peter J van Bladeren, John P Groten, Joop H J van Nesselrooij, Ben van Ommen
Source: Toxicologic pathology. 2005
View Full TextBenzene is an industrial chemical, component of automobile exhaust and cigarette smoke. After hepatic bioactivation benzene induces bone marrow, blood…
Authors: Wilbert H M Heijne, Diana Jonker, Rob H Stierum, Ben van Ommen, John P Groten
Source: Mutation research. 2005 Aug 4
View Full TextToxicogenomics can facilitate the identification and characterization of toxicity, as illustrated in this review. Toxicogenomics, the application of t…
Authors: Wilbert H M Heijne, Anne S Kienhuis, Ben van Ommen, Rob H Stierum, John P Groten
Source: Expert review of proteomics. 2005 Oct
View Full TextRats were exposed to three levels of bromobenzene, sampled at 6, 24, and 48 h, and liver gene expression profiles were determined to identify dose and…
Authors: Wilbert H M Heijne, Angela L Slitt, Peter J van Bladeren, John P Groten, Curtis D Klaassen, Rob H Stierum, Ben van Ommen
Source: Toxicological sciences : an official journal of the Society of Toxicology. 2004 Jun
View Full TextAuthors: Wilbert H M Heijne, Rob H Stierum, Winfried R Leeman, Ben van Ommen
Source: Cancer biomarkers : section A of Disease markers. 2005
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