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The WTCCC study identified 49 SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-4) - 1 x 10(-5) (tier 3). Here we show that three of…
Authors: Anne Barton, Wendy Thomson, Xiayi Ke, Steve Eyre, Anne Hinks, John Bowes, Darren Plant, Laura J Gibbons, Wellcome Trust Case Control Consortium, YEAR Consortium,…
Source: Nature genetics. 2008 Oct
View Free Full TextOBJECTIVE: To identify biomarkers in the first synovial fluid (SF) aspirate obtained from children with oligoarticular juvenile idiopathic arthritis (…
Authors: Patricia J Hunter, Kiran Nistala, Nipurna Jina, Ayad Eddaoudi, Wendy Thomson, Mike Hubank, Lucy R Wedderburn
Source: Arthritis and rheumatism. 2010 Mar
View Full TextTo discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs from 179 independent loci with P < 0.001 in a published meta-…
Authors: Soumya Raychaudhuri, Brian P Thomson, Elaine F Remmers, Stephen Eyre, Anne Hinks, Candace Guiducci, Joseph J Catanese, Gang Xie, Eli A Stahl, Robert Chen,…
Source: Nature genetics. 2009 Dec
View Full TextThe Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs putatively associated with rheumatoid arthritis at P = 1 x 10(-5) - 5 x…
Authors: Wendy Thomson, Anne Barton, Xiayi Ke, Steve Eyre, Anne Hinks, John Bowes, Rachelle Donn, Deborah Symmons, Samantha Hider, Ian N Bruce,…
Source: Nature genetics. 2007 Dec
View Free Full TextOBJECTIVES: /st> To determine if genetic variation in genes in the hypothalamic-pituitary-adrenal (HPA) axis, the primary stress response system, infl…
Authors: Kate L Holliday, Barbara I Nicholl, Gary J Macfarlane, Wendy Thomson, Kelly A Davies, John McBeth
Source: Annals of the rheumatic diseases. 2010 Mar
View Full TextOBJECTIVE: To examine the role of the variants of the PTPN22 and HLA-DRB1 genes as predictors of mortality in inflammatory polyarthritis (IP) and rheu…
Authors: Tracey M Farragher, Nicola J Goodson, Haris Naseem, Alan J Silman, Wendy Thomson, Deborah Symmons, Anne Barton
Source: Arthritis and rheumatism. 2008 Feb
View Full TextThe concept of susceptibility genes common to different autoimmune diseases is now firmly established with previous studies demonstrating overlap of l…
Authors: Anne Barton, Steve Eyre, Xiayi Ke, Anne Hinks, John Bowes, Edward Flynn, Paul Martin, YEAR Consortium, BIRAC Consortium, Anthony G Wilson,…
Source: Human molecular genetics. 2009 Jul 1
View Full TextOBJECTIVE: To investigate SLC26A2, the gene that causes diastrophic dysplasia, in juvenile idiopathic arthritis (JIA). METHODS: Nine polymorphisms acr…
Authors: Rebecca Lamb, Wendy Thomson, British Society of Paediatric and Adolescent Rheumatology, Emma M Ogilvie, Rachelle Donn
Source: Arthritis and rheumatism. 2007 Apr
View Full TextOBJECTIVE: Many classification systems for the HLA-DRB1 allelic association with rheumatoid arthritis (RA) have been reported, but few have been valid…
Authors: Ann W Morgan, Lubna Haroon-Rashid, Stephen G Martin, Hock-Chye Gooi, Jane Worthington, Wendy Thomson, Jennifer H Barrett, Paul Emery
Source: Arthritis and rheumatism. 2008 May
View Full TextOBJECTIVE: The majority of genetic risk factors for rheumatoid arthritis (RA) are associated with anti-citrullinated protein antibody (ACPA)-positive …
Authors: Diane van der Woude, Jeanine J Houwing-Duistermaat, René E M Toes, Tom W J Huizinga, Wendy Thomson, Jane Worthington, Annette H M van der Helm-van Mil, René R P de Vries
Source: Arthritis and rheumatism. 2009 Apr
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