10 literature results

• A role for adult TLX-positive neural stem cells in learning and behaviour.

  Neurogenesis persists in the adult brain and can be regulated by a plethora of external stimuli, such as learning, memory, exercise, environment and s…

  Authors: Chun-Li Zhang, Yuhua Zou, Weimin He, Fred H Gage, Ronald M Evans

  Source: Nature. 2008 Feb 21

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• Nuclear receptor expression links the circadian clock to metabolism.

  As sensors for fat-soluble hormones and dietary lipids, oscillations in nuclear receptor (NR) expression in key metabolic tissues may contribute to ci…

  Authors: Xiaoyong Yang, Michael Downes, Ruth T Yu, Angie L Bookout, Weimin He, Marty Straume, David J Mangelsdorf, Ronald M Evans

  Source: Cell. 2006 Aug 25

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• Muscle-specific Pparg deletion causes insulin resistance.

  Thiazolidinediones (TZDs) are insulin-sensitizing drugs and are potent agonists of the nuclear peroxisome proliferator-activated receptor-gamma (PPAR-…

  Authors: Andrea L Hevener, Weimin He, Yaacov Barak, Jamie Le, Gautam Bandyopadhyay, Peter Olson, Jason Wilkes, Ronald M Evans, Jerrold Olefsky

  Source: Nature medicine. 2003 Dec

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• Adipose tissue-specific PPARgamma deficiency increases resistance to oxidative stress.

  The nuclear hormone receptor peroxisome proliferator activated receptor gamma (PPARgamma) critically regulates adipogenesis and lipogenesis. Obesity i…

  Authors: Weijia Luo, Jin Cao, Jie Li, Weimin He

  Source: Experimental gerontology. 2008 Mar

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• PPARgamma2 Polymorphism and Human Health.

  The nuclear hormone receptor peroxisome proliferator activated receptor gamma (PPARgamma) is an important transcription factor regulating adipocyte di…

  Authors: Weimin He

  Source: PPAR research. 2009

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• Selective modulation of promoter recruitment and transcriptional activity of PPARgamma.

  Peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor regulated by the insulin-sensitizing thiazolidinediones (TZDs). We …

  Authors: Dorothy D Sears, Albert Hsiao, Jachelle M Ofrecio, Justin Chapman, Weimin He, Jerrold M Olefsky

  Source: Biochemical and biophysical research communications. 2007 Dec 21

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• ERRgamma directs and maintains the transition to oxidative metabolism in the postnatal heart.

  At birth, the heart undergoes a critical metabolic switch from a predominant dependence on carbohydrates during fetal life to a greater dependence on …

  Authors: William A Alaynick, Richard P Kondo, Wen Xie, Weimin He, Catherine R Dufour, Michael Downes, Johan W Jonker, Wayne Giles, Robert K Naviaux, Vincent Giguère,…

  Source: Cell metabolism. 2007 Jul

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• PPARdelta is a very low-density lipoprotein sensor in macrophages.

  Although triglyceride-rich particles, such as very low-density lipoprotein (VLDL), contribute significantly to human atherogenesis, the molecular basi…

  Authors: Ajay Chawla, Chih-Hao Lee, Yaacov Barak, Weimin He, John Rosenfeld, Debbie Liao, Jungyeob Han, Heonjoong Kang, Ronald M Evans

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2003 Feb 4

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• Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle.

  Syndrome X, typified by obesity, insulin resistance (IR), dyslipidemia, and other metabolic abnormalities, is responsive to antidiabetic thiazolidined…

  Authors: Weimin He, Yaacov Barak, Andrea Hevener, Peter Olson, Debbie Liao, Jamie Le, Michael Nelson, Estelita Ong, Jerrold M Olefsky, Ronald M Evans

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2003 Dec 23

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• Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer.

  Targeting of the nuclear prostaglandin receptor peroxisome proliferator-activated receptor delta (PPARdelta) by homologous recombination results in pl…

  Authors: Yaacov Barak, Debbie Liao, Weimin He, Estelita S Ong, Michael C Nelson, Jerrold M Olefsky, Richard Boland, Ronald M Evans

  Source: Proceedings of the National Academy of Sciences of the United States of America. 2002 Jan 8

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