1 to 10 of 79 literature results

• Urocortin and the brain.

  Urocortin is a member of the corticotropin-releasing hormone (CRH) family of peptides. In the brain, its potent suppression of food intake is mediated…

  Authors: Weihong Pan, Abba J Kastin

  Source: Progress in neurobiology. 2008 Feb

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• Tumor necrosis factor and stroke: role of the blood-brain barrier.

  The progression and outcome of stroke is affected by the intricate relationship between the blood-brain barrier (BBB) and tumor necrosis factor alpha …

  Authors: Weihong Pan, Abba J Kastin

  Source: Progress in neurobiology. 2007 Dec

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• Cytokine transport across the injured blood-spinal cord barrier.

  Spinal cord injury (SCI) induces dynamic changes of the blood-spinal cord barrier and even the more distant blood-brain barrier. Besides an immediate …

  Authors: Weihong Pan, Abba J Kastin

  Source: Current pharmaceutical design. 2008

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• Blood-brain barrier and feeding: regulatory roles of saturable transport systems for ingestive peptides.

  The two main ways for peptides in the peripheral body to enter the brain are by either saturable transport or passive diffusion across the blood-brain…

  Authors: Abba J Kastin, Weihong Pan

  Source: Current pharmaceutical design. 2008

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• Corticotropin-releasing hormone receptor-1 in cerebral microvessels changes during development and influences urocortin transport across the blood-brain barrier.

  In this study we tested the hypothesis that receptor-mediated transport of urocortin across the blood-brain barrier (BBB) undergoes developmental chan…

  Authors: Hung Hsuchou, Abba J Kastin, Xiaojun Wu, Hong Tu, Weihong Pan

  Source: Endocrinology. 2010 Mar

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• Permeation of blood-borne IL15 across the blood-brain barrier and the effect of LPS.

  Interleukin15 (IL 15) is a proinflammatory cytokine with elevated concentrations in autoimmune diseases involving the periphery (e.g. rheumatoid arthr…

  Authors: Weihong Pan, Hung Hsuchou, Chuanhui Yu, Abba J Kastin

  Source: Journal of neurochemistry. 2008 Jul

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• Developmental changes of leptin receptors in cerebral microvessels: unexpected relation to leptin transport.

  The adipokine leptin participates not only in the regulation of feeding and obesity in adults but also in neonatal development. It crosses the blood-b…

  Authors: Weihong Pan, Hung Hsuchou, Hong Tu, Abba J Kastin

  Source: Endocrinology. 2008 Mar

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• TNF reduces LIF endocytosis despite increasing NFkappaB-mediated gp130 expression.

  To examine how the proinflammatory cytokine tumor necrosis factor alpha (TNF) modulates the response of cerebral microvessels to other cytokines, we u…

  Authors: Chuanhui Yu, Abba J Kastin, Weihong Pan

  Source: Journal of cellular physiology. 2007 Oct

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• Convergent trafficking pattern of leptin after endocytosis mediated by ObRa-ObRd.

  The cellular effects of leptin are dependent on the receptor subtypes that mediate the signaling and fate of endocytosed leptin inside the cells. In t…

  Authors: Hong Tu, Weihong Pan, Laura Feucht, Abba J Kastin

  Source: Journal of cellular physiology. 2007 Jul

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• Cerebral microvascular IL15 is a novel mediator of TNF action.

  The blood-brain barrier is a gatekeeper and modulatory interface for the CNS. Cerebral endothelial cells are the major component of the blood-brain ba…

  Authors: Weihong Pan, Chuanhui Yu, Hung Hsuchou, Reas S Khan, Abba J Kastin

  Source: Journal of neurochemistry. 2009 Nov

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