1 to 10 of 21 literature results

• The NHL-domain protein Wech is crucial for the integrin-cytoskeleton link.

  Integrin transmembrane receptors mediate cell adhesion through intracellular linker proteins that connect to the cytoskeleton. Of the numerous linker …

  Authors: Birgit Löer, Reinhard Bauer, Roland Bornheim, Jessica Grell, Elisabeth Kremmer, Waldemar Kolanus, Michael Hoch

  Source: Nature cell biology. 2008 Apr

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• Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance.

  G proteins are an important class of regulatory switches in all living systems. They are activated by guanine nucleotide exchange factors (GEFs), whic…

  Authors: Markus Hafner, Anton Schmitz, Imke Grüne, Seergazhi G Srivatsan, Bianca Paul, Waldemar Kolanus, Thomas Quast, Elisabeth Kremmer, Inga Bauer, Michael Famulok

  Source: Nature. 2006 Dec 14

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• Guanine nucleotide exchange factors of the cytohesin family and their roles in signal transduction.

  Members of the cytohesin protein family, a group of guanine nucleotide exchange factors for adenosine diphosphate ribosylation factor (ARF) guanosine …

  Authors: Waldemar Kolanus

  Source: Immunological reviews. 2007 Aug

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• Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines.

  It is widely believed that rolling lymphocytes require successive chemokine-induced signaling for lymphocyte function-associated antigen 1 (LFA-1) to …

  Authors: Revital Shamri, Valentin Grabovsky, Jean-Marc Gauguet, Sara Feigelson, Eugenia Manevich, Waldemar Kolanus, Martyn K Robinson, Donald E Staunton, Ulrich H von Andrian, Ronen Alon

  Source: Nature immunology. 2005 May

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• A fundamental role of mAbp1 in neutrophils: impact on beta(2) integrin-mediated phagocytosis and adhesion in vivo.

  The mammalian actin-binding protein 1 (mAbp1, Hip-55, SH3P7) is phosphorylated by the nonreceptor tyrosine kinase Syk that has a fundamental effect fo…

  Authors: Jürgen Schymeinsky, Ronald Gerstl, Ingrid Mannigel, Katy Niedung, David Frommhold, Klaus Panthel, Jürgen Heesemann, Michael Sixt, Thomas Quast, Waldemar Kolanus,…

  Source: Blood. 2009 Nov 5

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• Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells.

  Adhesion and motility of mammalian leukocytes are essential requirements for innate and adaptive immune defense mechanisms. We show here that the guan…

  Authors: Thomas Quast, Barbara Tappertzhofen, Cora Schild, Jessica Grell, Niklas Czeloth, Reinhold Förster, Ronen Alon, Line Fraemohs, Katrin Dreck, Christian Weber,…

  Source: Blood. 2009 Jun 4

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• HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane.

  The Nef protein of human and simian immunodeficiency virus (HIV/SIV) is believed to interfere with T cell activation signals by forming a signaling co…

  Authors: Vanessa Witte, Bernd Laffert, Olaf Rosorius, Peter Lischka, Katja Blume, Gunther Galler, Andrea Stilper, Dieter Willbold, Paola D'Aloja, Michael Sixt,…

  Source: Molecular cell. 2004 Jan 30

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• A spectrum of biophysical interaction modes between T cells and different antigen-presenting cells during priming in 3-D collagen and in vivo.

  For activation T cells engage antigen-presenting cells (APCs) in lymphatic tissues. The contact duration and kinetics (static versus dynamic) vary con…

  Authors: Matthias Gunzer, Carsten Weishaupt, Anja Hillmer, Yasmin Basoglu, Peter Friedl, Kurt E Dittmar, Waldemar Kolanus, Georg Varga, Stephan Grabbe

  Source: Blood. 2004 Nov 1

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• Toxicity of ethylene combustion condensates is directly proportional to their carbon content.

  Numerous epidemiological studies have shown a strong link between air pollution and human morbidity and mortality. Combustion sources are most signifi…

  Authors: Nevena Stojicic, Christa Baumstark-Khan, Christine E Hellweg, Horst-Henning Grotheer, Günther Reitz, Waldemar Kolanus, Ruth Hemmersbach

  Source: Toxicology. 2010 Feb 28

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• Role of beta(3)-endonexin in the regulation of NF-kappaB-dependent expression of urokinase-type plasminogen activator receptor.

  Endothelial migration on extracellular matrix is regulated by integrins and proteolysis. Previous studies showed that beta(3)-integrins regulate expre…

  Authors: Felicitas Besta, Steffen Massberg, Korbinian Brand, Elke Müller, Sharon Page, Sabine Grüner, Michael Lorenz, Karin Sadoul, Waldemar Kolanus, Ernst Lengyel,…

  Source: Journal of cell science. 2002 Oct 15

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